Narrative review of local prostate and metastasis-directed radiotherapy in the treatment of metastatic prostate cancer

Naoki Terada; Rihito Aizawa; Keiji Nihei; Masaki Shiota; Takahiro Kojima; Takahiro Kimura; Takahiro Inoue; Hiroshi Kitamura; Mikio Sugimoto; Hiroyuki Nishiyama; Takashi Mizowaki; Toshiyuki Kamoto

doi:10.1093/jjco/hyac035

Narrative review of local prostate and metastasis-directed radiotherapy in the treatment of metastatic prostate cancer

Naoki Terada, Rihito Aizawa, Keiji Nihei, Masaki Shiota, Takahiro Kojima, Takahiro Kimura, Takahiro Inoue, Hiroshi Kitamura, Mikio Sugimoto, Hiroyuki Nishiyama, Takashi Mizowaki, Toshiyuki Kamoto

Urology

Research output: Contribution to journal › Review article › peer-review

Abstract

The role of local treatment in patients with de novo metastatic prostate cancer is controversial. In population-based retrospective studies, metastatic prostate cancer patients who received local treatment with prostate radiotherapy showed a better prognosis than those who did not. In addition, several prospective randomized studies demonstrated that prostate radiotherapy achieves a survival benefit for patients with oligo-metastasis. Moreover, the efficacy of metastasis-directed radiotherapy was evaluated, revealing a potential benefit for patients with oligo-metastasis. Importantly, these radiotherapies may reduce the occurrence of symptomatic local events. In this review, the rationale, efficacy and future perspectives for local prostate and metastasis-directed radiotherapy in the treatment of metastatic prostate cancer were described and summarized.

Original language	English
Pages (from-to)	633-641
Number of pages	9
Journal	Japanese journal of clinical oncology
Volume	52
Issue number	6
DOIs	https://doi.org/10.1093/jjco/hyac035
Publication status	Published - May 31 2022

All Science Journal Classification (ASJC) codes

Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1093/jjco/hyac035

Cite this

Terada, N., Aizawa, R., Nihei, K., Shiota, M., Kojima, T., Kimura, T., Inoue, T., Kitamura, H., Sugimoto, M., Nishiyama, H., Mizowaki, T., & Kamoto, T. (2022). Narrative review of local prostate and metastasis-directed radiotherapy in the treatment of metastatic prostate cancer. Japanese journal of clinical oncology, 52(6), 633-641. https://doi.org/10.1093/jjco/hyac035

Terada, N, Aizawa, R, Nihei, K, Shiota, M, Kojima, T, Kimura, T, Inoue, T, Kitamura, H, Sugimoto, M, Nishiyama, H, Mizowaki, T & Kamoto, T 2022, 'Narrative review of local prostate and metastasis-directed radiotherapy in the treatment of metastatic prostate cancer', Japanese journal of clinical oncology, vol. 52, no. 6, pp. 633-641. https://doi.org/10.1093/jjco/hyac035

@article{1a84585993d44a3c81b767f6907f6597,

title = "Narrative review of local prostate and metastasis-directed radiotherapy in the treatment of metastatic prostate cancer",

abstract = "The role of local treatment in patients with de novo metastatic prostate cancer is controversial. In population-based retrospective studies, metastatic prostate cancer patients who received local treatment with prostate radiotherapy showed a better prognosis than those who did not. In addition, several prospective randomized studies demonstrated that prostate radiotherapy achieves a survival benefit for patients with oligo-metastasis. Moreover, the efficacy of metastasis-directed radiotherapy was evaluated, revealing a potential benefit for patients with oligo-metastasis. Importantly, these radiotherapies may reduce the occurrence of symptomatic local events. In this review, the rationale, efficacy and future perspectives for local prostate and metastasis-directed radiotherapy in the treatment of metastatic prostate cancer were described and summarized.",

author = "Naoki Terada and Rihito Aizawa and Keiji Nihei and Masaki Shiota and Takahiro Kojima and Takahiro Kimura and Takahiro Inoue and Hiroshi Kitamura and Mikio Sugimoto and Hiroyuki Nishiyama and Takashi Mizowaki and Toshiyuki Kamoto",

year = "2022",

month = may,

day = "31",

doi = "10.1093/jjco/hyac035",

language = "English",

volume = "52",

pages = "633--641",

journal = "Japanese Journal of Clinical Oncology",

issn = "0368-2811",

publisher = "Oxford University Press",

number = "6",

}

TY - JOUR

T1 - Narrative review of local prostate and metastasis-directed radiotherapy in the treatment of metastatic prostate cancer

AU - Terada, Naoki

AU - Aizawa, Rihito

AU - Nihei, Keiji

AU - Shiota, Masaki

AU - Kojima, Takahiro

AU - Kimura, Takahiro

AU - Inoue, Takahiro

AU - Kitamura, Hiroshi

AU - Sugimoto, Mikio

AU - Nishiyama, Hiroyuki

AU - Mizowaki, Takashi

AU - Kamoto, Toshiyuki

PY - 2022/5/31

Y1 - 2022/5/31

N2 - The role of local treatment in patients with de novo metastatic prostate cancer is controversial. In population-based retrospective studies, metastatic prostate cancer patients who received local treatment with prostate radiotherapy showed a better prognosis than those who did not. In addition, several prospective randomized studies demonstrated that prostate radiotherapy achieves a survival benefit for patients with oligo-metastasis. Moreover, the efficacy of metastasis-directed radiotherapy was evaluated, revealing a potential benefit for patients with oligo-metastasis. Importantly, these radiotherapies may reduce the occurrence of symptomatic local events. In this review, the rationale, efficacy and future perspectives for local prostate and metastasis-directed radiotherapy in the treatment of metastatic prostate cancer were described and summarized.

AB - The role of local treatment in patients with de novo metastatic prostate cancer is controversial. In population-based retrospective studies, metastatic prostate cancer patients who received local treatment with prostate radiotherapy showed a better prognosis than those who did not. In addition, several prospective randomized studies demonstrated that prostate radiotherapy achieves a survival benefit for patients with oligo-metastasis. Moreover, the efficacy of metastasis-directed radiotherapy was evaluated, revealing a potential benefit for patients with oligo-metastasis. Importantly, these radiotherapies may reduce the occurrence of symptomatic local events. In this review, the rationale, efficacy and future perspectives for local prostate and metastasis-directed radiotherapy in the treatment of metastatic prostate cancer were described and summarized.

UR - http://www.scopus.com/inward/record.url?scp=85131217488&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85131217488&partnerID=8YFLogxK

U2 - 10.1093/jjco/hyac035

DO - 10.1093/jjco/hyac035

M3 - Review article

C2 - 35325157

AN - SCOPUS:85131217488

SN - 0368-2811

VL - 52

SP - 633

EP - 641

JO - Japanese Journal of Clinical Oncology

JF - Japanese Journal of Clinical Oncology

IS - 6

ER -

Narrative review of local prostate and metastasis-directed radiotherapy in the treatment of metastatic prostate cancer

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this