Neural basis of photo/chromatic sensitivity in adolescence

Takao Yamasaki, Yoshinobu Goto, Naoko Kinukawa, Shozo Tobimatsu

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Purpose: To determine a psychophysiological basis for age visual sensitivity to chromatic and achromatic stimuli. Methods: We investigated the effects of achromatic and four isoluminant color combinations (blue/red, blue/green, green/red, and blue/yellow), luminance ratio changes in color combinations (blue/red; 1:1, 3:4, 4:3) and contrast changes (3 to 100%) on steady-state electroretinograms (ERGs) and visual evoked potentials (VEPs) in 32 healthy teenagers and 30 young adults. Results: We found that (1) dual peaks at 9 and 18 Hz with a dip at 12 Hz were observed in VEPs with all isoluminant color combinations, (2) VEP responses were significantly enhanced and the 12-Hz dip became unclear with luminance ratio changes between two colors with a nonantagonistic relationship (blue/red), and (3) VEP amplitudes were significantly increased when the contrast was increased. These characteristics were more evident in teenagers than young adults; however, ERGs were qualitatively similar between the two groups. Discussion: The visual cortex is differently modulated by different color-luminance combinations, and higher sensitivity to color-luminance combinations in the visual cortex in teenagers is responsible for the high prevalence of photo/chromatic sensitivity in adolescence.

Original languageEnglish
Pages (from-to)1611-1618
Number of pages8
Issue number9
Publication statusPublished - Sep 2008

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology


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