Neuritogenic activity of gangliosides from echinoderms and their structure-activity relationship

Masafumi Kaneko, Koji Yamada, Tomofumi Miyamoto, Masanori Inagaki, Ryuichi Higuchi

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

The effects of the gangliosides isolated from echinoderms on the neuritogenesis of a rat pheochromocytoma cell line (PC-12 cells) in the presence of nerve growth factor were investigated. The results show that they displayed neuritogenic activity. Based on the observed results, a structure-activity relationship has been established.

Original languageEnglish
Pages (from-to)462-463
Number of pages2
JournalChemical and Pharmaceutical Bulletin
Volume55
Issue number3
DOIs
Publication statusPublished - Mar 1 2007

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

Fingerprint Dive into the research topics of 'Neuritogenic activity of gangliosides from echinoderms and their structure-activity relationship'. Together they form a unique fingerprint.

Cite this