Neurological disorders identified during treatment of a SARS-cov-2 infection

Shinichi Wada; Yoji Nagasaki; Yoko Arimizu; Masatoshi Shimo; Yuta Matsukuma; Masaki Okamoto; Shinichiro Yoshida; Ikkei Ohashi; Go Hashimoto; Takahiro Kuwashiro; Masahiro Yasaka; Yasushi Okada

doi:10.2169/internalmedicine.5447-20

Neurological disorders identified during treatment of a SARS-cov-2 infection

Shinichi Wada, Yoji Nagasaki, Yoko Arimizu, Masatoshi Shimo, Yuta Matsukuma, Masaki Okamoto, Shinichiro Yoshida, Ikkei Ohashi, Go Hashimoto, Takahiro Kuwashiro, Masahiro Yasaka, Yasushi Okada

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

A 69-year-old man was admitted to our hospital under diagnosis of pneumonia due to severe acute respiratory syndrome-corona virus 2 (SARS-CoV-2) (Day 0). He underwent endotracheal intubation from Day 3. Although his respiratory condition improved and anesthetic drugs were discontinued, no cough reflex was observed despite intubation having been performed until Day 17. His tendon reflexes were also diminished. We suspected that he had developed Guillain-Barré syndrome (GBS), and administered intravenous immunoglobulin from Day 18. The absence of cough reflex improved and extubation was successfully performed on Day 23. Neurological disorders including GBS should be considered when intubated SARS-CoV-2 patients present with a loss of cough reflex during the treatment period.

Original language	English
Pages (from-to)	2187-2189
Number of pages	3
Journal	Internal Medicine
Volume	59
Issue number	17
DOIs	https://doi.org/10.2169/internalmedicine.5447-20
Publication status	Published - Sept 1 2020
Externally published	Yes

All Science Journal Classification (ASJC) codes

Internal Medicine

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10.2169/internalmedicine.5447-20

Cite this

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title = "Neurological disorders identified during treatment of a SARS-cov-2 infection",

abstract = "A 69-year-old man was admitted to our hospital under diagnosis of pneumonia due to severe acute respiratory syndrome-corona virus 2 (SARS-CoV-2) (Day 0). He underwent endotracheal intubation from Day 3. Although his respiratory condition improved and anesthetic drugs were discontinued, no cough reflex was observed despite intubation having been performed until Day 17. His tendon reflexes were also diminished. We suspected that he had developed Guillain-Barr{\'e} syndrome (GBS), and administered intravenous immunoglobulin from Day 18. The absence of cough reflex improved and extubation was successfully performed on Day 23. Neurological disorders including GBS should be considered when intubated SARS-CoV-2 patients present with a loss of cough reflex during the treatment period.",

author = "Shinichi Wada and Yoji Nagasaki and Yoko Arimizu and Masatoshi Shimo and Yuta Matsukuma and Masaki Okamoto and Shinichiro Yoshida and Ikkei Ohashi and Go Hashimoto and Takahiro Kuwashiro and Masahiro Yasaka and Yasushi Okada",

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doi = "10.2169/internalmedicine.5447-20",

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TY - JOUR

T1 - Neurological disorders identified during treatment of a SARS-cov-2 infection

AU - Wada, Shinichi

AU - Nagasaki, Yoji

AU - Arimizu, Yoko

AU - Shimo, Masatoshi

AU - Matsukuma, Yuta

AU - Okamoto, Masaki

AU - Yoshida, Shinichiro

AU - Ohashi, Ikkei

AU - Hashimoto, Go

AU - Kuwashiro, Takahiro

AU - Yasaka, Masahiro

AU - Okada, Yasushi

PY - 2020/9/1

Y1 - 2020/9/1

N2 - A 69-year-old man was admitted to our hospital under diagnosis of pneumonia due to severe acute respiratory syndrome-corona virus 2 (SARS-CoV-2) (Day 0). He underwent endotracheal intubation from Day 3. Although his respiratory condition improved and anesthetic drugs were discontinued, no cough reflex was observed despite intubation having been performed until Day 17. His tendon reflexes were also diminished. We suspected that he had developed Guillain-Barré syndrome (GBS), and administered intravenous immunoglobulin from Day 18. The absence of cough reflex improved and extubation was successfully performed on Day 23. Neurological disorders including GBS should be considered when intubated SARS-CoV-2 patients present with a loss of cough reflex during the treatment period.

AB - A 69-year-old man was admitted to our hospital under diagnosis of pneumonia due to severe acute respiratory syndrome-corona virus 2 (SARS-CoV-2) (Day 0). He underwent endotracheal intubation from Day 3. Although his respiratory condition improved and anesthetic drugs were discontinued, no cough reflex was observed despite intubation having been performed until Day 17. His tendon reflexes were also diminished. We suspected that he had developed Guillain-Barré syndrome (GBS), and administered intravenous immunoglobulin from Day 18. The absence of cough reflex improved and extubation was successfully performed on Day 23. Neurological disorders including GBS should be considered when intubated SARS-CoV-2 patients present with a loss of cough reflex during the treatment period.

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SP - 2187

EP - 2189

JO - Internal Medicine

JF - Internal Medicine

IS - 17

ER -

Neurological disorders identified during treatment of a SARS-cov-2 infection

Abstract

All Science Journal Classification (ASJC) codes

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