Neurosurgical management and pathology of lumbosacral lipomas with tethered cord

Takato Morioka, Nobuya Murakami, Takafumi Shimogawa, Nobutaka Mukae, Kimiaki Hashiguchi, Satoshi Suzuki, Koji Iihara

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Lumbosacral lipomas are the most common form of occult spinal dysraphism. The development of lumbosacral lipomas is from the premature disjunction of the neural tube from the surrounding ectoderm, leaving the neural plate open posteriorly and allowing for the infiltration of mesodermal tissue, including fatty tissue. Since lumbosacral lipomas are a common cause of spinal cord tethering that can lead to progressive neurological deficits, prophylactic neurosurgery for lumbosacral lipomas, including untethering of the spinal cord, is recommended. We briefly review the embryology, classification, clinical presentation, imaging evaluation, surgical indication, neurosurgical management and pathological examination that are involved in recognizing these complicated malformative pathologies.

Original languageEnglish
Pages (from-to)385-392
Number of pages8
JournalNeuropathology
Volume37
Issue number5
DOIs
Publication statusPublished - Oct 1 2017

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Lipoma
Pathology
Spinal Cord
Neural Plate
Ectoderm
Neural Tube
Embryology
Neural Tube Defects
Neurosurgery
Adipose Tissue

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Clinical Neurology

Cite this

Neurosurgical management and pathology of lumbosacral lipomas with tethered cord. / Morioka, Takato; Murakami, Nobuya; Shimogawa, Takafumi; Mukae, Nobutaka; Hashiguchi, Kimiaki; Suzuki, Satoshi; Iihara, Koji.

In: Neuropathology, Vol. 37, No. 5, 01.10.2017, p. 385-392.

Research output: Contribution to journalReview article

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