Abstract
Lumbosacral lipomas are the most common form of occult spinal dysraphism. The development of lumbosacral lipomas is from the premature disjunction of the neural tube from the surrounding ectoderm, leaving the neural plate open posteriorly and allowing for the infiltration of mesodermal tissue, including fatty tissue. Since lumbosacral lipomas are a common cause of spinal cord tethering that can lead to progressive neurological deficits, prophylactic neurosurgery for lumbosacral lipomas, including untethering of the spinal cord, is recommended. We briefly review the embryology, classification, clinical presentation, imaging evaluation, surgical indication, neurosurgical management and pathological examination that are involved in recognizing these complicated malformative pathologies.
| Original language | English |
|---|---|
| Pages (from-to) | 385-392 |
| Number of pages | 8 |
| Journal | Neuropathology |
| Volume | 37 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Oct 2017 |
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All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Clinical Neurology
Cite this
Neurosurgical management and pathology of lumbosacral lipomas with tethered cord. / Morioka, Takato; Murakami, Nobuya; Shimogawa, Takafumi; Mukae, Nobutaka; Hashiguchi, Kimiakai; Suzuki, Satoshi O.; Iihara, Koji.
In: Neuropathology, Vol. 37, No. 5, 10.2017, p. 385-392.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Neurosurgical management and pathology of lumbosacral lipomas with tethered cord
AU - Morioka, Takato
AU - Murakami, Nobuya
AU - Shimogawa, Takafumi
AU - Mukae, Nobutaka
AU - Hashiguchi, Kimiakai
AU - Suzuki, Satoshi O.
AU - Iihara, Koji
PY - 2017/10
Y1 - 2017/10
N2 - Lumbosacral lipomas are the most common form of occult spinal dysraphism. The development of lumbosacral lipomas is from the premature disjunction of the neural tube from the surrounding ectoderm, leaving the neural plate open posteriorly and allowing for the infiltration of mesodermal tissue, including fatty tissue. Since lumbosacral lipomas are a common cause of spinal cord tethering that can lead to progressive neurological deficits, prophylactic neurosurgery for lumbosacral lipomas, including untethering of the spinal cord, is recommended. We briefly review the embryology, classification, clinical presentation, imaging evaluation, surgical indication, neurosurgical management and pathological examination that are involved in recognizing these complicated malformative pathologies.
AB - Lumbosacral lipomas are the most common form of occult spinal dysraphism. The development of lumbosacral lipomas is from the premature disjunction of the neural tube from the surrounding ectoderm, leaving the neural plate open posteriorly and allowing for the infiltration of mesodermal tissue, including fatty tissue. Since lumbosacral lipomas are a common cause of spinal cord tethering that can lead to progressive neurological deficits, prophylactic neurosurgery for lumbosacral lipomas, including untethering of the spinal cord, is recommended. We briefly review the embryology, classification, clinical presentation, imaging evaluation, surgical indication, neurosurgical management and pathological examination that are involved in recognizing these complicated malformative pathologies.
UR - http://www.scopus.com/inward/record.url?scp=85017638825&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85017638825&partnerID=8YFLogxK
U2 - 10.1111/neup.12382
DO - 10.1111/neup.12382
M3 - Review article
C2 - 28387433
AN - SCOPUS:85017638825
VL - 37
SP - 385
EP - 392
JO - Neuropathology
JF - Neuropathology
SN - 0919-6544
IS - 5
ER -