Neurosurgical management of occult spinal dysraphism associated with OEIS complex

Takato Morioka, Kimiaki Hashiguchi, Fumiaki Yoshida, Kenichi Matsumoto, Yasushi Miyagi, Shinji Nagata, Takashi Yoshiura, Kouji Masumoto, Tomoaki Taguchi, Tomio Sasaki

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Abstract

Introduction: OEIS complex has been described as a combination of defects consisting of o mphalocele (O), e xstrophy of the cloaca (E), imperforate anus (I), and s pinal defects (S). As the first three defects are life-threatening and treated on a priority basis, neurosurgical intervention for spinal defects is deferred until recuperation from abdominogenital repair. However, the best timing for neurosurgical operation has not been precisely described. Materials and methods: We reviewed our neurosurgical management of three cases (case 1: myelomeningocele; cases 2 and 3: terminal myelocystocele). At 2-6 (3.6 on average) months after birth, neurosurgical procedures, including reduction of the size of the lumbosacral cystic lesion and untethering of the spinal cord, were performed. Results: During this period, the patients' weights increased from 1,911 to 3,368 g on average, and the lumbosacral cystic lesion was markedly enlarged. In all cases, no neurological deterioration was seen, and ventriculoperitoneal shunt was not indicated. Conclusion: Thus, neurosurgical procedures can be performed in patients weighing 3-4 kg and/or at an age of 3 months, after confirming recuperated conditions from abdominogenital repair. Careful observation should be made of the size of the lumbosacral cystic lesion and neurological deterioration.

Original languageEnglish
Pages (from-to)723-729
Number of pages7
JournalChild's Nervous System
Volume24
Issue number6
DOIs
Publication statusPublished - Jun 1 2008

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All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Morioka, T., Hashiguchi, K., Yoshida, F., Matsumoto, K., Miyagi, Y., Nagata, S., ... Sasaki, T. (2008). Neurosurgical management of occult spinal dysraphism associated with OEIS complex. Child's Nervous System, 24(6), 723-729. https://doi.org/10.1007/s00381-007-0519-y