New cytotoxic spongian diterpenes from the sponge Dysidea cf. arenaria

Mika Agena, Chiaki Tanaka, Novriyandi Hanif, Mina Yasumoto-Hirose, Junichi Tanaka

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

Seven new (1-7) and three known (8-10) spongian-class diterpenes have been isolated from the sponge Dysidea cf. arenaria collected in Okinawa. Compound 6 was also isolated from the nudibranch Chromodoris kuniei. The structures of the new entities were elucidated by spectroscopic analyses. Three of the new spongians (2, 6, and 7) showed cytotoxicity against NBT-T2 rat bladder epithelial cells.

Original languageEnglish
Pages (from-to)1495-1499
Number of pages5
JournalTetrahedron
Volume65
Issue number7
DOIs
Publication statusPublished - Feb 14 2009
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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