New dimeric morphine from opium poppy (Papaver somuniferum) and its physiological function

Satoshi Morimoto, Kazunari Suemori, Futoshi Taura, Yukihiro Shoyama

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15 Citations (Scopus)

Abstract

Together with bismorphine A (1), a new compound bismorphine B (2) was identified in the wounded capsules of Papaver somniferum. On the basis of analyses of the various spectral data, bismorphine B (2) was determined as a novel morphinan alkaloid, in which two morphine units are coupled through a biphenyl ether bond. When the physiological function of bismorphine B (2) in opium poppy was investigated, it was evident that this alkaloid more effectively cross-links cell wall polysaccharide pectins than bismorphine A (1) and that such cross-linking reaction leads to resistance against hydrolysis by pectinase.

Original languageEnglish
Pages (from-to)987-989
Number of pages3
JournalJournal of Natural Products
Volume66
Issue number7
DOIs
Publication statusPublished - Jul 1 2003

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All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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