New dimeric morphine from opium poppy (Papaver somuniferum) and its physiological function

Satoshi Morimoto, Kazunari Suemori, Futoshi Taura, Yukihiro Shoyama

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


Together with bismorphine A (1), a new compound bismorphine B (2) was identified in the wounded capsules of Papaver somniferum. On the basis of analyses of the various spectral data, bismorphine B (2) was determined as a novel morphinan alkaloid, in which two morphine units are coupled through a biphenyl ether bond. When the physiological function of bismorphine B (2) in opium poppy was investigated, it was evident that this alkaloid more effectively cross-links cell wall polysaccharide pectins than bismorphine A (1) and that such cross-linking reaction leads to resistance against hydrolysis by pectinase.

Original languageEnglish
Pages (from-to)987-989
Number of pages3
JournalJournal of Natural Products
Issue number7
Publication statusPublished - Jul 1 2003

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


Dive into the research topics of 'New dimeric morphine from opium poppy (Papaver somuniferum) and its physiological function'. Together they form a unique fingerprint.

Cite this