TY - JOUR
T1 - New isoindolinones from the fruiting bodies of the fungus Hericium erinaceus
AU - Ashour, Ahmed
AU - Amen, Yhiya
AU - Allam, Ahmed E.
AU - Kudo, Takashi
AU - Nagata, Maki
AU - Ohnuki, Koichiro
AU - Shimizu, Kuniyoshi
N1 - Publisher Copyright:
© 2019 Phytochemical Society of Europe
PY - 2019/8
Y1 - 2019/8
N2 - Two new isoindolin-1-ones, named erinacerin (M–N) along with eleven known compounds have been isolated from the fruiting bodies of the medicinal mushroom Hericium erinaceus. The structures of compounds were elucidated based on spectroscopic studies and comparison with the known related ones. The anticancer potential of the isolates were tested with an in vitro cytotoxic assay against six human cancer cell lines (SH-SY5Y, 1321N1, HCT-116, Caco-2, OVK18 and HeLa).
AB - Two new isoindolin-1-ones, named erinacerin (M–N) along with eleven known compounds have been isolated from the fruiting bodies of the medicinal mushroom Hericium erinaceus. The structures of compounds were elucidated based on spectroscopic studies and comparison with the known related ones. The anticancer potential of the isolates were tested with an in vitro cytotoxic assay against six human cancer cell lines (SH-SY5Y, 1321N1, HCT-116, Caco-2, OVK18 and HeLa).
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U2 - 10.1016/j.phytol.2019.04.017
DO - 10.1016/j.phytol.2019.04.017
M3 - Article
AN - SCOPUS:85064927027
VL - 32
SP - 10
EP - 14
JO - Phytochemistry Letters
JF - Phytochemistry Letters
SN - 1874-3900
ER -
