New isoindolinones from the fruiting bodies of the fungus Hericium erinaceus

Ahmed Ashour; Yhiya Amen; Ahmed E. Allam; Takashi Kudo; Maki Nagata; Koichiro Ohnuki; Kuniyoshi Shimizu

doi:10.1016/j.phytol.2019.04.017

New isoindolinones from the fruiting bodies of the fungus Hericium erinaceus

Ahmed Ashour, Yhiya Amen, Ahmed E. Allam, Takashi Kudo, Maki Nagata, Koichiro Ohnuki, Kuniyoshi Shimizu

Sustainable Bioresources Science

Research output: Contribution to journal › Article › peer-review

Abstract

Two new isoindolin-1-ones, named erinacerin (M–N) along with eleven known compounds have been isolated from the fruiting bodies of the medicinal mushroom Hericium erinaceus. The structures of compounds were elucidated based on spectroscopic studies and comparison with the known related ones. The anticancer potential of the isolates were tested with an in vitro cytotoxic assay against six human cancer cell lines (SH-SY5Y, 1321N1, HCT-116, Caco-2, OVK18 and HeLa).

Original language	English
Pages (from-to)	10-14
Number of pages	5
Journal	Phytochemistry Letters
Volume	32
DOIs	https://doi.org/10.1016/j.phytol.2019.04.017
Publication status	Published - Aug 1 2019

All Science Journal Classification (ASJC) codes

Biotechnology
Biochemistry
Agronomy and Crop Science
Plant Science

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abstract = "Two new isoindolin-1-ones, named erinacerin (M–N) along with eleven known compounds have been isolated from the fruiting bodies of the medicinal mushroom Hericium erinaceus. The structures of compounds were elucidated based on spectroscopic studies and comparison with the known related ones. The anticancer potential of the isolates were tested with an in vitro cytotoxic assay against six human cancer cell lines (SH-SY5Y, 1321N1, HCT-116, Caco-2, OVK18 and HeLa).",

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AU - Ashour, Ahmed

AU - Amen, Yhiya

AU - Allam, Ahmed E.

AU - Kudo, Takashi

AU - Nagata, Maki

AU - Ohnuki, Koichiro

AU - Shimizu, Kuniyoshi

PY - 2019/8/1

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