New methodological approaches for assessing thrombus formation in cardiovascular disease

Kazuya Hosokawa; Tomoko Ohnishi-Wada; Tomoka Nagasato; Hisayo Sameshima-Kaneko; Chiaki Oyamada; Jeffrey Dahlen

doi:10.33963/KP.15493

New methodological approaches for assessing thrombus formation in cardiovascular disease

Kazuya Hosokawa, Tomoko Ohnishi-Wada, Tomoka Nagasato, Hisayo Sameshima-Kaneko, Chiaki Oyamada, Jeffrey Dahlen

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Abstract

Antiplatelet therapy is the mainstay preventive strategy for cardiovascular diseases, and dual antiplatelet therapy comprising aspirin and a P2Y12 inhibitor is the standard treatment for patients who underwent percutaneous coronary intervention. The Total Thrombus-Formation Analysis System (T.TAS) is a microchip flow.chamber system developed to evaluate overall thrombus formation under flow conditions, which is reportedly able to assess single and combined antithrombotic therapy. Here, we focus on this new system, T-TAS, and review its characteristics together with those of the conventional systems available for evaluation of antithrombotic therapies for cardiovascular diseases.

Original language	English
Pages (from-to)	667-673
Number of pages	7
Journal	Kardiologia Polska
Volume	78
Issue number	78
DOIs	https://doi.org/10.33963/KP.15493
Publication status	Published - May 12 2020
Externally published	Yes

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.33963/KP.15493

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title = "New methodological approaches for assessing thrombus formation in cardiovascular disease",

abstract = "Antiplatelet therapy is the mainstay preventive strategy for cardiovascular diseases, and dual antiplatelet therapy comprising aspirin and a P2Y12 inhibitor is the standard treatment for patients who underwent percutaneous coronary intervention. The Total Thrombus-Formation Analysis System (T.TAS) is a microchip flow.chamber system developed to evaluate overall thrombus formation under flow conditions, which is reportedly able to assess single and combined antithrombotic therapy. Here, we focus on this new system, T-TAS, and review its characteristics together with those of the conventional systems available for evaluation of antithrombotic therapies for cardiovascular diseases. ",

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AU - Hosokawa, Kazuya

AU - Ohnishi-Wada, Tomoko

AU - Nagasato, Tomoka

AU - Sameshima-Kaneko, Hisayo

AU - Oyamada, Chiaki

AU - Dahlen, Jeffrey

PY - 2020/5/12

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N2 - Antiplatelet therapy is the mainstay preventive strategy for cardiovascular diseases, and dual antiplatelet therapy comprising aspirin and a P2Y12 inhibitor is the standard treatment for patients who underwent percutaneous coronary intervention. The Total Thrombus-Formation Analysis System (T.TAS) is a microchip flow.chamber system developed to evaluate overall thrombus formation under flow conditions, which is reportedly able to assess single and combined antithrombotic therapy. Here, we focus on this new system, T-TAS, and review its characteristics together with those of the conventional systems available for evaluation of antithrombotic therapies for cardiovascular diseases.

AB - Antiplatelet therapy is the mainstay preventive strategy for cardiovascular diseases, and dual antiplatelet therapy comprising aspirin and a P2Y12 inhibitor is the standard treatment for patients who underwent percutaneous coronary intervention. The Total Thrombus-Formation Analysis System (T.TAS) is a microchip flow.chamber system developed to evaluate overall thrombus formation under flow conditions, which is reportedly able to assess single and combined antithrombotic therapy. Here, we focus on this new system, T-TAS, and review its characteristics together with those of the conventional systems available for evaluation of antithrombotic therapies for cardiovascular diseases.

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New methodological approaches for assessing thrombus formation in cardiovascular disease

Abstract

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