New methodological approaches for assessing thrombus formation in cardiovascular disease

Kazuya Hosokawa, Tomoko Ohnishi-Wada, Tomoka Nagasato, Hisayo Sameshima-Kaneko, Chiaki Oyamada, Jeffrey Dahlen

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)


Antiplatelet therapy is the mainstay preventive strategy for cardiovascular diseases, and dual antiplatelet therapy comprising aspirin and a P2Y12 inhibitor is the standard treatment for patients who underwent percutaneous coronary intervention. The Total Thrombus-Formation Analysis System (T.TAS) is a microchip flow.chamber system developed to evaluate overall thrombus formation under flow conditions, which is reportedly able to assess single and combined antithrombotic therapy. Here, we focus on this new system, T-TAS, and review its characteristics together with those of the conventional systems available for evaluation of antithrombotic therapies for cardiovascular diseases.

Original languageEnglish
Pages (from-to)667-673
Number of pages7
JournalKardiologia Polska
Issue number78
Publication statusPublished - May 12 2020
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine


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