New methodological approaches for assessing thrombus formation in cardiovascular disease

Kazuya Hosokawa, Tomoko Ohnishi-Wada, Tomoka Nagasato, Hisayo Sameshima-Kaneko, Chiaki Oyamada, Jeffrey Dahlen

Research output: Contribution to journalArticlepeer-review


Antiplatelet therapy is the mainstay preventive strategy for cardiovascular diseases, and dual antiplatelet therapy comprising aspirin and a P2Y12 inhibitor is the standard treatment for patients who underwent percutaneous coronary intervention. The Total Thrombus‑Formation Analysis System (T‑TAS) is a microchip flow‑chamber system developed to evaluate overall thrombus formation under flow conditions, which is reportedly able to assess single and combined antithrombotic therapy. Here, we focus on this new system, T‑TAS, and review its characteristics together with those of the conventional systems available for evaluation of antithrombotic therapies for cardiovascular diseases.

Original languageEnglish
Pages (from-to)667-673
Number of pages7
JournalKardiologia Polska
Issue number7-8
Publication statusPublished - Aug 25 2020

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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