TY - JOUR
T1 - New methodological approaches for assessing thrombus formation in cardiovascular disease
AU - Hosokawa, Kazuya
AU - Ohnishi-Wada, Tomoko
AU - Nagasato, Tomoka
AU - Sameshima-Kaneko, Hisayo
AU - Oyamada, Chiaki
AU - Dahlen, Jeffrey
N1 - Publisher Copyright:
© 2020 by the Author(s).
PY - 2020/5/12
Y1 - 2020/5/12
N2 - Antiplatelet therapy is the mainstay preventive strategy for cardiovascular diseases, and dual antiplatelet therapy comprising aspirin and a P2Y12 inhibitor is the standard treatment for patients who underwent percutaneous coronary intervention. The Total Thrombus-Formation Analysis System (T.TAS) is a microchip flow.chamber system developed to evaluate overall thrombus formation under flow conditions, which is reportedly able to assess single and combined antithrombotic therapy. Here, we focus on this new system, T-TAS, and review its characteristics together with those of the conventional systems available for evaluation of antithrombotic therapies for cardiovascular diseases.
AB - Antiplatelet therapy is the mainstay preventive strategy for cardiovascular diseases, and dual antiplatelet therapy comprising aspirin and a P2Y12 inhibitor is the standard treatment for patients who underwent percutaneous coronary intervention. The Total Thrombus-Formation Analysis System (T.TAS) is a microchip flow.chamber system developed to evaluate overall thrombus formation under flow conditions, which is reportedly able to assess single and combined antithrombotic therapy. Here, we focus on this new system, T-TAS, and review its characteristics together with those of the conventional systems available for evaluation of antithrombotic therapies for cardiovascular diseases.
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U2 - 10.33963/KP.15493
DO - 10.33963/KP.15493
M3 - Review article
C2 - 32633476
AN - SCOPUS:85090075973
VL - 78
SP - 667
EP - 673
JO - Kardiologia Polska
JF - Kardiologia Polska
SN - 0022-9032
IS - 78
ER -