Abstract
Two new oxoindolo diterpene epimers, anthcolorin G 1 and anthcolorin H 2, nine new meroterpenes, (7R,8R)-8-hydroxysydowic acid 4, (7S,10S)-10-hydroxy-sydowic acid 5, (7S,11R)-12-hydroxy-sydowic acid 6, (7S,11R)-12-acetoxy-sydowic acid 7, (7R,8R)-1,8-epoxy-11-hydroxy-sydonic acid 9, 7-deoxy-7,14-didehydro-11-hydroxy-sydonic acid 11, 7-deoxy-7,14-didehydro-12-acetoxy-sydonic acid 14, and (E)-7-deoxy-7,8-didehydro-12-acetoxy-sydonic acid 15, (7R)-11-hydroxy-sydonic acid methyl ester 18, and a benzoic acid derivative, isolated for the first time from a natural source, 3-hydroxy-4-(1-oxo-ethane)benzoic acid 10, in addition to twelve known compounds were isolated from the solid rice culture of the endophytic fungus Aspergillus versicolor. Their structures were determined by one- and two-dimensional NMR spectroscopy, high resolution electrospray ionization mass and circular dichroism spectra. Their cytotoxic activity was evaluated using Hela cells.
| Original language | English |
|---|---|
| Pages (from-to) | 70-76 |
| Number of pages | 7 |
| Journal | Phytochemistry Letters |
| Volume | 32 |
| DOIs | |
| Publication status | Published - Aug 2019 |
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All Science Journal Classification (ASJC) codes
- Biotechnology
- Biochemistry
- Agronomy and Crop Science
- Plant Science
Cite this
New secondary metabolites from the mangrove endophytic fungus Aspergillus versicolor. / Elsbaey, Marwa; Tanaka, Chiaki; Miyamoto, Tomofumi.
In: Phytochemistry Letters, Vol. 32, 08.2019, p. 70-76.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - New secondary metabolites from the mangrove endophytic fungus Aspergillus versicolor
AU - Elsbaey, Marwa
AU - Tanaka, Chiaki
AU - Miyamoto, Tomofumi
PY - 2019/8
Y1 - 2019/8
N2 - Two new oxoindolo diterpene epimers, anthcolorin G 1 and anthcolorin H 2, nine new meroterpenes, (7R,8R)-8-hydroxysydowic acid 4, (7S,10S)-10-hydroxy-sydowic acid 5, (7S,11R)-12-hydroxy-sydowic acid 6, (7S,11R)-12-acetoxy-sydowic acid 7, (7R,8R)-1,8-epoxy-11-hydroxy-sydonic acid 9, 7-deoxy-7,14-didehydro-11-hydroxy-sydonic acid 11, 7-deoxy-7,14-didehydro-12-acetoxy-sydonic acid 14, and (E)-7-deoxy-7,8-didehydro-12-acetoxy-sydonic acid 15, (7R)-11-hydroxy-sydonic acid methyl ester 18, and a benzoic acid derivative, isolated for the first time from a natural source, 3-hydroxy-4-(1-oxo-ethane)benzoic acid 10, in addition to twelve known compounds were isolated from the solid rice culture of the endophytic fungus Aspergillus versicolor. Their structures were determined by one- and two-dimensional NMR spectroscopy, high resolution electrospray ionization mass and circular dichroism spectra. Their cytotoxic activity was evaluated using Hela cells.
AB - Two new oxoindolo diterpene epimers, anthcolorin G 1 and anthcolorin H 2, nine new meroterpenes, (7R,8R)-8-hydroxysydowic acid 4, (7S,10S)-10-hydroxy-sydowic acid 5, (7S,11R)-12-hydroxy-sydowic acid 6, (7S,11R)-12-acetoxy-sydowic acid 7, (7R,8R)-1,8-epoxy-11-hydroxy-sydonic acid 9, 7-deoxy-7,14-didehydro-11-hydroxy-sydonic acid 11, 7-deoxy-7,14-didehydro-12-acetoxy-sydonic acid 14, and (E)-7-deoxy-7,8-didehydro-12-acetoxy-sydonic acid 15, (7R)-11-hydroxy-sydonic acid methyl ester 18, and a benzoic acid derivative, isolated for the first time from a natural source, 3-hydroxy-4-(1-oxo-ethane)benzoic acid 10, in addition to twelve known compounds were isolated from the solid rice culture of the endophytic fungus Aspergillus versicolor. Their structures were determined by one- and two-dimensional NMR spectroscopy, high resolution electrospray ionization mass and circular dichroism spectra. Their cytotoxic activity was evaluated using Hela cells.
UR - http://www.scopus.com/inward/record.url?scp=85065551901&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85065551901&partnerID=8YFLogxK
U2 - 10.1016/j.phytol.2019.04.023
DO - 10.1016/j.phytol.2019.04.023
M3 - Article
AN - SCOPUS:85065551901
VL - 32
SP - 70
EP - 76
JO - Phytochemistry Letters
JF - Phytochemistry Letters
SN - 1874-3900
ER -