Abstract
To investigate the relationship between neuronal activity and hemodynamics, we carried out a near-infrared spectroscopy (NIRS) study to measure the regional changes of hemoglobin concentration associated with cortical activation in the human sensorimotor cortex (SMI) to both voluntary and nonvoluntary tasks. We measured the hemodynamic evoked responses to voluntary finger movement and nonvoluntary electrical stimulation applied on the fingers (thumb and ring finger, respectively). Measurements were performed on 6 healthy right-handed volunteers using block paradigms and we analyzed both the spatial/temporal features and the magnitude of the optical signal induced by cerebral activation during these protocols. We constantly observed an increase in the cerebral concentration of oxygenated hemoglobin at the cortical side contralateral to the stimulated side. Our findings are in agreement with results in positron emission tomography (PET), functional magnetic resonance imaging (fMRI) and EEG (Electroencephalogram).
| Original language | English |
|---|---|
| Pages (from-to) | 2492-2495 |
| Number of pages | 4 |
| Journal | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| Publication status | Published - 2007 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics
Cite this
NIRS measurement of hemodynamic evoked responses in the primary sensorimotor cortex. / Xu, Mingdi; Takata, Hirotsugu; Ge, Sheng; Hayami, Takehito; Yamasaki, Takao; Tobimatsu, Shozo; Iramina, Keiji.
In: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 2007, p. 2492-2495.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - NIRS measurement of hemodynamic evoked responses in the primary sensorimotor cortex.
AU - Xu, Mingdi
AU - Takata, Hirotsugu
AU - Ge, Sheng
AU - Hayami, Takehito
AU - Yamasaki, Takao
AU - Tobimatsu, Shozo
AU - Iramina, Keiji
PY - 2007
Y1 - 2007
N2 - To investigate the relationship between neuronal activity and hemodynamics, we carried out a near-infrared spectroscopy (NIRS) study to measure the regional changes of hemoglobin concentration associated with cortical activation in the human sensorimotor cortex (SMI) to both voluntary and nonvoluntary tasks. We measured the hemodynamic evoked responses to voluntary finger movement and nonvoluntary electrical stimulation applied on the fingers (thumb and ring finger, respectively). Measurements were performed on 6 healthy right-handed volunteers using block paradigms and we analyzed both the spatial/temporal features and the magnitude of the optical signal induced by cerebral activation during these protocols. We constantly observed an increase in the cerebral concentration of oxygenated hemoglobin at the cortical side contralateral to the stimulated side. Our findings are in agreement with results in positron emission tomography (PET), functional magnetic resonance imaging (fMRI) and EEG (Electroencephalogram).
AB - To investigate the relationship between neuronal activity and hemodynamics, we carried out a near-infrared spectroscopy (NIRS) study to measure the regional changes of hemoglobin concentration associated with cortical activation in the human sensorimotor cortex (SMI) to both voluntary and nonvoluntary tasks. We measured the hemodynamic evoked responses to voluntary finger movement and nonvoluntary electrical stimulation applied on the fingers (thumb and ring finger, respectively). Measurements were performed on 6 healthy right-handed volunteers using block paradigms and we analyzed both the spatial/temporal features and the magnitude of the optical signal induced by cerebral activation during these protocols. We constantly observed an increase in the cerebral concentration of oxygenated hemoglobin at the cortical side contralateral to the stimulated side. Our findings are in agreement with results in positron emission tomography (PET), functional magnetic resonance imaging (fMRI) and EEG (Electroencephalogram).
UR - http://www.scopus.com/inward/record.url?scp=84903853761&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84903853761&partnerID=8YFLogxK
M3 - Article
C2 - 18002500
SP - 2492
EP - 2495
JO - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
JF - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SN - 1557-170X
ER -