To investigate the effect of nitric oxide (NO) on food intake in the chicken, l-NG-nitro-arginine methyl ester HC1 (l-NNA), an inhibitor of NO synthase, was applied. When i.p. administered, l-NNA significantly inhibited the food intake of broiler chickens in a dose response manner. Food ingestion was also depressed by the i.c.v. injection of l-NNA in a dose response fashion. The effect of l-NNA was attenuated by i.c.v. administration of l-arginine. These results suggest that central NO may control feeding behavior in the chicken.
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Clinical Neurology
- Developmental Biology