No preventive effect of dietary fiber against colon cancer in the Japanese population: A cross-sectional analysis

Shigeyuki Nakaji, Tadashi Shimoyama, Seiko Wada, Kazuo Sugawara, Shoji Tokunaga, Domhnall MacAuley, David Baxter

Research output: Contribution to journalArticle

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Abstract

The report of Fuchs et al. in 1999 on the protective effects of dietary fiber (DF) against colon carcinogenesis has led many researchers to question the benefits of DF. We analyzed the relationship between dietary intake and mortality from colon cancer in Japan cross-sectionally. Dietary data were taken from the National Nutrition Survey. The standardized mortality ratio (SMR) was calculated using data from "Vital Statistics" and "the Population Census in Japan." Multiple regression analysis (stepwise variable selection method) was performed with the SMR of colon cancer as the objective variable and intake of DF, nutrients, and food groups in 1966 as the explanatory variables. The beta regression coefficient was significantly positive for intakes of fat, protein, and vitamin C and significantly negative for intakes of calcium and vitamin A to the SMR of colon cancer However, no significant correlation was observed for DF or for any of the various food groups analyzed. In conclusion, our data do not demonstrate any protective effect of DF on colon cancer in subjects with a low fat intake (Japanese subjects), which supports Fuchs' findings in subjects with high fat intake (U.S. subjects).

Original languageEnglish
Pages (from-to)156-159
Number of pages4
JournalNutrition and Cancer
Volume45
Issue number2
DOIs
Publication statusPublished - Jan 1 2003

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Dietary Fiber
Colonic Neoplasms
Cross-Sectional Studies
Mortality
Population
Fats
Food
Japan
Vital Statistics
Nutrition Surveys
Censuses
Protein C
Vitamin A
Ascorbic Acid
Colon
Carcinogenesis
Regression Analysis
Research Personnel
Calcium

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Oncology
  • Nutrition and Dietetics
  • Cancer Research

Cite this

Nakaji, S., Shimoyama, T., Wada, S., Sugawara, K., Tokunaga, S., MacAuley, D., & Baxter, D. (2003). No preventive effect of dietary fiber against colon cancer in the Japanese population: A cross-sectional analysis. Nutrition and Cancer, 45(2), 156-159. https://doi.org/10.1207/S15327914NC4502_03

No preventive effect of dietary fiber against colon cancer in the Japanese population : A cross-sectional analysis. / Nakaji, Shigeyuki; Shimoyama, Tadashi; Wada, Seiko; Sugawara, Kazuo; Tokunaga, Shoji; MacAuley, Domhnall; Baxter, David.

In: Nutrition and Cancer, Vol. 45, No. 2, 01.01.2003, p. 156-159.

Research output: Contribution to journalArticle

Nakaji, S, Shimoyama, T, Wada, S, Sugawara, K, Tokunaga, S, MacAuley, D & Baxter, D 2003, 'No preventive effect of dietary fiber against colon cancer in the Japanese population: A cross-sectional analysis', Nutrition and Cancer, vol. 45, no. 2, pp. 156-159. https://doi.org/10.1207/S15327914NC4502_03
Nakaji, Shigeyuki ; Shimoyama, Tadashi ; Wada, Seiko ; Sugawara, Kazuo ; Tokunaga, Shoji ; MacAuley, Domhnall ; Baxter, David. / No preventive effect of dietary fiber against colon cancer in the Japanese population : A cross-sectional analysis. In: Nutrition and Cancer. 2003 ; Vol. 45, No. 2. pp. 156-159.
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