Non-invasive examinations successfully select patients with medical temporal lobe epilepsy for anterior temporal lobectomy

T. Morioka, S. Nishio, T. Kawamura, K. Fukui, M. Sasaki, M. Fukui

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1 Citation (Scopus)

Abstract

We retrospectively analyzed 8 patients with intractable medial temporal lobe epilepsy (MTLE) who underwent the anterior temporal lobectomy with hippocampectomy (ATL) without invasive examinations such as chronic subdural electrode recording. Five patients had a history of febrile convulsion. While all 8 patients had oral automatism, automatism of ipsilateral limbs with dystonic posture of contralateral limbs was demonstrated in 2 patients. Bilateral temporal paroxysmal activities on interictal EEG was observed in 4 patients and all patients had clear ictal onset zone on unilateral anterior temporal region. MRI demonstrated unilateral hippocampal sclerosis in 5 cases. Interictal FDG-PET depicted hypometabolism of the unilateral temporal lobe in all cases, however, ECD-SPECT failed to reveal the hypoperfusion of the unilateral temporal lobe in a case. Postoperatively, 7 cases became seizure free, and one had rare seizure. Non-invasive examinations, especially ictal EEG and concordant FDG-PET findings, in patients with oral automatism in seizure semiology, successfully select patients with MTLE for ATL.

Original languageEnglish
Pages (from-to)559-565
Number of pages7
JournalBrain and Nerve
Volume53
Issue number6
Publication statusPublished - 2001

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

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