Novel acylated triterpene glycosides from Muraltia heisteria

Mohamed Elbandy, Tomofumi Miyamoto, Bruno Chauffert, Clément Delaude, Marie Aleth Lacaille-Dubois

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21 Citations (Scopus)

Abstract

Four new acylated triterpene glycosides (1-4) have been isolated as two inseparable mixtures of the trans- and cis-3,4,5-trimethoxycinnamoyl derivatives (1,2 and 3,4) from the roots of Muraltia heisteria. The structures of these compounds were elucidated by various 1D and 2D NMR techniques, including 1H and 13C, COSY, NOESY, HSQC, TOCSY, and HMBC experiments and FABMS: Compounds 3 and 4 were shown to be cytotoxic in a human colon cancer cell line but did not show any ability to potentiate in vitro cisplatin cytotoxicity.

Original languageEnglish
Pages (from-to)193-197
Number of pages5
JournalJournal of Natural Products
Volume65
Issue number2
DOIs
Publication statusPublished - Mar 6 2002

All Science Journal Classification (ASJC) codes

  • Plant Science
  • Chemistry (miscellaneous)
  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

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    Elbandy, M., Miyamoto, T., Chauffert, B., Delaude, C., & Lacaille-Dubois, M. A. (2002). Novel acylated triterpene glycosides from Muraltia heisteria. Journal of Natural Products, 65(2), 193-197. https://doi.org/10.1021/np010381+