The guest-binding behaviour of a novel cage-type azaparacyclophane, which has been prepared by the reaction of N,N′,N″,N‴-tetravalyl-1, 6,20,25-tetraaza[220.127.116.11]paracyclophane with N,N′,N″,N‴- tetrakis(5-carboxynicotinoyl)-2,11,20,29-tetraaza[18.104.22.168]paracyclophane, was examined in aqueous media and evaluated by a computer-aided molecular modelling study on the basis of molecular mechanics (MM2 and MMP2) and molecular dynamics (AMBER and CHARMM) conformational search.
|Number of pages||3|
|Journal||Journal of the Chemical Society, Chemical Communications|
|Publication status||Published - Dec 1 1991|
All Science Journal Classification (ASJC) codes
- Molecular Medicine