Novel calcium ionophores: Supramolecular complexation by the hydroxylated-bistetrahydrofuran skeleton of potent antitumor Annonaceous acetogenins

Shigeki Sasaki, Hiroyuki Naito, Katsunori Maruta, Eiji Kawahara, Minoru Maeda

Research output: Contribution to journalArticlepeer-review

42 Citations (Scopus)

Abstract

Hydroxylated bistetrahydrofuran derivatives which are structural components of potent antitumor Annonaceous acetogenins have been revealed to form supramolecular complexes with metal cations. In particular, 2b formed 2:1 ligand/metal complex with calcium cation with high selectivity.

Original languageEnglish
Pages (from-to)3337-3340
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number20
DOIs
Publication statusPublished - May 16 1994

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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