Novel DNA-polysaccharide triple helixes and their application to a gene carrier

Kazuo Sakurai; Seiji Shinkai

doi:10.1023/A:1014463712915

Novel DNA-polysaccharide triple helixes and their application to a gene carrier

Kazuo Sakurai, Seiji Shinkai

Institute for Advanced Study

Research output: Contribution to journal › Article

6 Citations (Scopus)

Abstract

Schizophyllan is a polysaccharide that belongs to the β-(1 → 3)-glucan family and has been known to activate the immunity system. This paper reviews our recent finding that schizophyllan can form a macromolecular complex with single-stranded polynucleotides and this complex is applicable to a new class of gene carriers.

Original language	English
Pages (from-to)	173-178
Number of pages	6
Journal	Journal of Inclusion Phenomena
Volume	41
Issue number	1-4
DOIs	https://doi.org/10.1023/A:1014463712915
Publication status	Published - Dec 1 2001

All Science Journal Classification (ASJC) codes

Food Science
Chemistry(all)
Condensed Matter Physics

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abstract = "Schizophyllan is a polysaccharide that belongs to the β-(1 → 3)-glucan family and has been known to activate the immunity system. This paper reviews our recent finding that schizophyllan can form a macromolecular complex with single-stranded polynucleotides and this complex is applicable to a new class of gene carriers.",

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