Novel physically adsorbed polymer coating on PMMA microchip with multi channel array for high-throughput protein analysis

Hiroki Okada, Noritada Kaji, Manabu Tokeshi, Yoshinobu Baba

Research output: Contribution to conferencePaperpeer-review

Abstract

For protein analysis, polymeric microchip was extremely incompatible with protein samples. To overcome the incompatibility, we developed a novel physically adsorbed polymer coating, which was a new approach and different from conventional coating methods, on PMMA microchip using cellulose derivatives as the coating reagents. The coating method remarkably progressed analytical performance and we could successfully separate 5 proteins dependent of their own sizes with high reproducibility (RSD; within 3 %, n=12) on coated PMMA microchip with 12 channels array.

Original languageEnglish
Pages401-403
Number of pages3
Publication statusPublished - Jan 1 2006
Externally publishedYes
Event10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan
Duration: Nov 5 2006Nov 9 2006

Other

Other10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
Country/TerritoryJapan
CityTokyo
Period11/5/0611/9/06

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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