Nuclear matrix association regions of rat α2-macroglobulin gene

Takashi Ito, Yoshiyuki Sakaki

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We have identified DNA fragments which bind specifically to the nuclear matrix in vitro, termed matrix association regions (MARs), in the first and fourth introns of rat α2-macroglobulin gene. The MAR in the first intron is enriched with sequences closely related to the cleavage consensus of topoisomerase II, and contains the binding site of nuclear factor-α, a sequence-specific DNA binding protein reported previously.

Original languageEnglish
Pages (from-to)449-454
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume149
Issue number2
DOIs
Publication statusPublished - Dec 16 1987

Fingerprint

Nuclear Matrix
Macroglobulins
Introns
Rats
Genes
Type II DNA Topoisomerase
DNA-Binding Proteins
Binding Sites
DNA
In Vitro Techniques

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Nuclear matrix association regions of rat α2-macroglobulin gene. / Ito, Takashi; Sakaki, Yoshiyuki.

In: Biochemical and Biophysical Research Communications, Vol. 149, No. 2, 16.12.1987, p. 449-454.

Research output: Contribution to journalArticle

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