Numerical simulation of high intensity focused ultrasound therapy with volume model of human body

Kohei Okita, Kazuyasu Sugiyama, Kenji Ono, Shu Takagi, Yoichiro Matsumoto

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The development of the HIFU therapy for the deeply placed cancer has been desired. On problem is the displacement of the focal point due to the inhomogeneity of human body. The objectives are to realize the appropriate phase control of an array transducer and to support the preoperative planning of HIFU therapy by the computational prediction of treatment regions. Our approach is to solve the mass and momentum equations for mixture with the equation of state of media. The heat equation with a heat source of a viscous dissipation is solved to estimate the ablation region of tissue. The ablation, i.e., the heat denaturation of protein, is modeled as a phase transition by the phase field model. The HIFU therapy with a bowl-shape array transducer for a liver cancer is simulated. As the result with a phase control, we obtain a clear focus which is closer to a target point than the focus without a phase control, when the ultrasound propagates through lib bones. In addition, the development of the ablation region is reproduced numerically.

Original languageEnglish
Title of host publication9th International Symposium on Therapeutic Ultrasound - ISTU 2009
Pages371-374
Number of pages4
Volume1215
DOIs
Publication statusPublished - Mar 30 2010
Externally publishedYes
Event9th International Symposium on Therapeutic Ultrasound, ISTU 2009 - Aix-en-Provence, France
Duration: Sep 24 2009Sep 26 2009

Other

Other9th International Symposium on Therapeutic Ultrasound, ISTU 2009
CountryFrance
CityAix-en-Provence
Period9/24/099/26/09

Fingerprint

phase control
human body
ablation
therapy
transducers
cancer
simulation
biopolymer denaturation
heat sources
liver
bones
planning
inhomogeneity
equations of state
dissipation
proteins
momentum
heat
thermodynamics
estimates

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

Cite this

Okita, K., Sugiyama, K., Ono, K., Takagi, S., & Matsumoto, Y. (2010). Numerical simulation of high intensity focused ultrasound therapy with volume model of human body. In 9th International Symposium on Therapeutic Ultrasound - ISTU 2009 (Vol. 1215, pp. 371-374) https://doi.org/10.1063/1.3367184

Numerical simulation of high intensity focused ultrasound therapy with volume model of human body. / Okita, Kohei; Sugiyama, Kazuyasu; Ono, Kenji; Takagi, Shu; Matsumoto, Yoichiro.

9th International Symposium on Therapeutic Ultrasound - ISTU 2009. Vol. 1215 2010. p. 371-374.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Okita, K, Sugiyama, K, Ono, K, Takagi, S & Matsumoto, Y 2010, Numerical simulation of high intensity focused ultrasound therapy with volume model of human body. in 9th International Symposium on Therapeutic Ultrasound - ISTU 2009. vol. 1215, pp. 371-374, 9th International Symposium on Therapeutic Ultrasound, ISTU 2009, Aix-en-Provence, France, 9/24/09. https://doi.org/10.1063/1.3367184
Okita K, Sugiyama K, Ono K, Takagi S, Matsumoto Y. Numerical simulation of high intensity focused ultrasound therapy with volume model of human body. In 9th International Symposium on Therapeutic Ultrasound - ISTU 2009. Vol. 1215. 2010. p. 371-374 https://doi.org/10.1063/1.3367184
Okita, Kohei ; Sugiyama, Kazuyasu ; Ono, Kenji ; Takagi, Shu ; Matsumoto, Yoichiro. / Numerical simulation of high intensity focused ultrasound therapy with volume model of human body. 9th International Symposium on Therapeutic Ultrasound - ISTU 2009. Vol. 1215 2010. pp. 371-374
@inproceedings{ec73474c693249e484722c08455713ed,
title = "Numerical simulation of high intensity focused ultrasound therapy with volume model of human body",
abstract = "The development of the HIFU therapy for the deeply placed cancer has been desired. On problem is the displacement of the focal point due to the inhomogeneity of human body. The objectives are to realize the appropriate phase control of an array transducer and to support the preoperative planning of HIFU therapy by the computational prediction of treatment regions. Our approach is to solve the mass and momentum equations for mixture with the equation of state of media. The heat equation with a heat source of a viscous dissipation is solved to estimate the ablation region of tissue. The ablation, i.e., the heat denaturation of protein, is modeled as a phase transition by the phase field model. The HIFU therapy with a bowl-shape array transducer for a liver cancer is simulated. As the result with a phase control, we obtain a clear focus which is closer to a target point than the focus without a phase control, when the ultrasound propagates through lib bones. In addition, the development of the ablation region is reproduced numerically.",
author = "Kohei Okita and Kazuyasu Sugiyama and Kenji Ono and Shu Takagi and Yoichiro Matsumoto",
year = "2010",
month = "3",
day = "30",
doi = "10.1063/1.3367184",
language = "English",
isbn = "9780735407589",
volume = "1215",
pages = "371--374",
booktitle = "9th International Symposium on Therapeutic Ultrasound - ISTU 2009",

}

TY - GEN

T1 - Numerical simulation of high intensity focused ultrasound therapy with volume model of human body

AU - Okita, Kohei

AU - Sugiyama, Kazuyasu

AU - Ono, Kenji

AU - Takagi, Shu

AU - Matsumoto, Yoichiro

PY - 2010/3/30

Y1 - 2010/3/30

N2 - The development of the HIFU therapy for the deeply placed cancer has been desired. On problem is the displacement of the focal point due to the inhomogeneity of human body. The objectives are to realize the appropriate phase control of an array transducer and to support the preoperative planning of HIFU therapy by the computational prediction of treatment regions. Our approach is to solve the mass and momentum equations for mixture with the equation of state of media. The heat equation with a heat source of a viscous dissipation is solved to estimate the ablation region of tissue. The ablation, i.e., the heat denaturation of protein, is modeled as a phase transition by the phase field model. The HIFU therapy with a bowl-shape array transducer for a liver cancer is simulated. As the result with a phase control, we obtain a clear focus which is closer to a target point than the focus without a phase control, when the ultrasound propagates through lib bones. In addition, the development of the ablation region is reproduced numerically.

AB - The development of the HIFU therapy for the deeply placed cancer has been desired. On problem is the displacement of the focal point due to the inhomogeneity of human body. The objectives are to realize the appropriate phase control of an array transducer and to support the preoperative planning of HIFU therapy by the computational prediction of treatment regions. Our approach is to solve the mass and momentum equations for mixture with the equation of state of media. The heat equation with a heat source of a viscous dissipation is solved to estimate the ablation region of tissue. The ablation, i.e., the heat denaturation of protein, is modeled as a phase transition by the phase field model. The HIFU therapy with a bowl-shape array transducer for a liver cancer is simulated. As the result with a phase control, we obtain a clear focus which is closer to a target point than the focus without a phase control, when the ultrasound propagates through lib bones. In addition, the development of the ablation region is reproduced numerically.

UR - http://www.scopus.com/inward/record.url?scp=77949910643&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77949910643&partnerID=8YFLogxK

U2 - 10.1063/1.3367184

DO - 10.1063/1.3367184

M3 - Conference contribution

AN - SCOPUS:77949910643

SN - 9780735407589

VL - 1215

SP - 371

EP - 374

BT - 9th International Symposium on Therapeutic Ultrasound - ISTU 2009

ER -