Nutritional assessment in patients with pulmonary nontuberculous mycobacteriosis

Satoshi Ikegame, Sanae Maki, Kentaro Wakamatsu, Nobuhiko Nagata, Hiroyuki Kumazoe, Masaki Fujita, Yoichi Nakanishi, Masayuki Kawasaki, Akira Kajiki

Research output: Contribution to journalArticle

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Abstract

Objective To determine the nutritional factors that influence disease spread in patients with pulmonary Mycobacterium avium complex (MAC) infection. Methods A prospective observational study. Patients Patients with pulmonary MAC infection were enrolled in this study. Chest computed tomography (CT), abdominal CT, and physical, clinical, and nutritional laboratory data were collected after obtaining informed consent. Results Seventy-eight patients (16 males and 62 females) were consecutively enrolled. While the mean body mass index (BMI) was low (19.6 ± 2.7 kg/m 2), the mean serum albumin concentration was within normal range (4.2 ± 0.2 g/dL). We evaluated the number of affected lung segments to define the degree of disease spread, and examined the relationships between various parameters and disease spread. Multivariate analysis identified the duration of the disease (+1.6 segment/100 months, p=0.03), BMI (-0.5 segment/BMI, p=0.003), and white blood cell count (+0.7 segment/1,000 WBC, p=0.03) as factors contributing to disease spread. Conclusion BMI is an excellent marker for nutritional assessment and for predicting disease spread in patients with pulmonary MAC infection.

Original languageEnglish
Pages (from-to)2541-2546
Number of pages6
JournalInternal Medicine
Volume50
Issue number21
DOIs
Publication statusPublished - Nov 9 2011

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Nutrition Assessment
Mycobacterium avium Complex
Lung
Body Mass Index
Infection
Tomography
Informed Consent
Leukocyte Count
Serum Albumin
Observational Studies
Reference Values
Thorax
Multivariate Analysis
Prospective Studies

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Ikegame, S., Maki, S., Wakamatsu, K., Nagata, N., Kumazoe, H., Fujita, M., ... Kajiki, A. (2011). Nutritional assessment in patients with pulmonary nontuberculous mycobacteriosis. Internal Medicine, 50(21), 2541-2546. https://doi.org/10.2169/internalmedicine.50.5853

Nutritional assessment in patients with pulmonary nontuberculous mycobacteriosis. / Ikegame, Satoshi; Maki, Sanae; Wakamatsu, Kentaro; Nagata, Nobuhiko; Kumazoe, Hiroyuki; Fujita, Masaki; Nakanishi, Yoichi; Kawasaki, Masayuki; Kajiki, Akira.

In: Internal Medicine, Vol. 50, No. 21, 09.11.2011, p. 2541-2546.

Research output: Contribution to journalArticle

Ikegame, S, Maki, S, Wakamatsu, K, Nagata, N, Kumazoe, H, Fujita, M, Nakanishi, Y, Kawasaki, M & Kajiki, A 2011, 'Nutritional assessment in patients with pulmonary nontuberculous mycobacteriosis', Internal Medicine, vol. 50, no. 21, pp. 2541-2546. https://doi.org/10.2169/internalmedicine.50.5853
Ikegame S, Maki S, Wakamatsu K, Nagata N, Kumazoe H, Fujita M et al. Nutritional assessment in patients with pulmonary nontuberculous mycobacteriosis. Internal Medicine. 2011 Nov 9;50(21):2541-2546. https://doi.org/10.2169/internalmedicine.50.5853
Ikegame, Satoshi ; Maki, Sanae ; Wakamatsu, Kentaro ; Nagata, Nobuhiko ; Kumazoe, Hiroyuki ; Fujita, Masaki ; Nakanishi, Yoichi ; Kawasaki, Masayuki ; Kajiki, Akira. / Nutritional assessment in patients with pulmonary nontuberculous mycobacteriosis. In: Internal Medicine. 2011 ; Vol. 50, No. 21. pp. 2541-2546.
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