Abstract
PURPOSE. We examined the intrascleral and retrobulbar blood vessels in highly myopic eyes by swept-source optical coherence tomography (swept-source OCT). METHODS. We included in the study 662 of 357 patients with pathologic myopia (spherical equivalent of myopic refractive error ≥ 8.00 diopters or axial length. 26.5 mm). A sweptsource OCT system that uses a wavelength sweeping laser with A-scan repetition rate of 100,000 Hz and 1 lm wavelength was used. Radial scans along 12 meridians of 12 mm scan length centered on the fovea were made. Indocyanine green angiography (ICGA) also was performed to identify the intrascleral and retrobulbar vessels that were observed by swept-source OCT. RESULTS. Intrascleral and retrobulbar blood vessels were observed in the macular area of the highly myopic eyes. Linear hyporeflective structures running in the sclera were observed in 474 of the 662 myopic eyes, and ICGA confirmed that these structures were the long posterior ciliary arteries (LPCAs) or the short posterior ciliary arteries (SPCAs) whose entry sites into the eye were displaced toward the temporal edge of the posterior staphyloma in 50 eyes. In 36 of the 662 eyes (5.4%), cross sections of the blood vessels were seen coursing through the scleral layer. In 177 of these 443 eyes, the retrobulbar posterior ciliary arteries (PCAs) also were observed as a cluster of circular or curved hyporeflectant structures just posterior to the sclera. CONCLUSIONS. Swept-source OCT is a high-quality method to detect intrascleral and retroscleral blood vessels in the eyes with pathologic myopia. These findings and longitudinal studies of these vessels will help in investigating how they are altered in pathologic myopia, and how such alterations are related to the complications in the retina-choroid and optic nerve.
| Original language | English |
|---|---|
| Pages (from-to) | 7290-7298 |
| Number of pages | 9 |
| Journal | Investigative Ophthalmology and Visual Science |
| Volume | 53 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - Oct 1 2012 |
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All Science Journal Classification (ASJC) codes
- Ophthalmology
- Sensory Systems
- Cellular and Molecular Neuroscience
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Observations of vascular structures within and posterior to sclera in eyes with pathologic myopia by swept-source optical coherence tomography. / Ohno-Matsui, Kyoko; Akiba, Masahiro; Ishibashi, Tatsuro; Moriyama, Muka.
In: Investigative Ophthalmology and Visual Science, Vol. 53, No. 11, 01.10.2012, p. 7290-7298.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Observations of vascular structures within and posterior to sclera in eyes with pathologic myopia by swept-source optical coherence tomography
AU - Ohno-Matsui, Kyoko
AU - Akiba, Masahiro
AU - Ishibashi, Tatsuro
AU - Moriyama, Muka
PY - 2012/10/1
Y1 - 2012/10/1
N2 - PURPOSE. We examined the intrascleral and retrobulbar blood vessels in highly myopic eyes by swept-source optical coherence tomography (swept-source OCT). METHODS. We included in the study 662 of 357 patients with pathologic myopia (spherical equivalent of myopic refractive error ≥ 8.00 diopters or axial length. 26.5 mm). A sweptsource OCT system that uses a wavelength sweeping laser with A-scan repetition rate of 100,000 Hz and 1 lm wavelength was used. Radial scans along 12 meridians of 12 mm scan length centered on the fovea were made. Indocyanine green angiography (ICGA) also was performed to identify the intrascleral and retrobulbar vessels that were observed by swept-source OCT. RESULTS. Intrascleral and retrobulbar blood vessels were observed in the macular area of the highly myopic eyes. Linear hyporeflective structures running in the sclera were observed in 474 of the 662 myopic eyes, and ICGA confirmed that these structures were the long posterior ciliary arteries (LPCAs) or the short posterior ciliary arteries (SPCAs) whose entry sites into the eye were displaced toward the temporal edge of the posterior staphyloma in 50 eyes. In 36 of the 662 eyes (5.4%), cross sections of the blood vessels were seen coursing through the scleral layer. In 177 of these 443 eyes, the retrobulbar posterior ciliary arteries (PCAs) also were observed as a cluster of circular or curved hyporeflectant structures just posterior to the sclera. CONCLUSIONS. Swept-source OCT is a high-quality method to detect intrascleral and retroscleral blood vessels in the eyes with pathologic myopia. These findings and longitudinal studies of these vessels will help in investigating how they are altered in pathologic myopia, and how such alterations are related to the complications in the retina-choroid and optic nerve.
AB - PURPOSE. We examined the intrascleral and retrobulbar blood vessels in highly myopic eyes by swept-source optical coherence tomography (swept-source OCT). METHODS. We included in the study 662 of 357 patients with pathologic myopia (spherical equivalent of myopic refractive error ≥ 8.00 diopters or axial length. 26.5 mm). A sweptsource OCT system that uses a wavelength sweeping laser with A-scan repetition rate of 100,000 Hz and 1 lm wavelength was used. Radial scans along 12 meridians of 12 mm scan length centered on the fovea were made. Indocyanine green angiography (ICGA) also was performed to identify the intrascleral and retrobulbar vessels that were observed by swept-source OCT. RESULTS. Intrascleral and retrobulbar blood vessels were observed in the macular area of the highly myopic eyes. Linear hyporeflective structures running in the sclera were observed in 474 of the 662 myopic eyes, and ICGA confirmed that these structures were the long posterior ciliary arteries (LPCAs) or the short posterior ciliary arteries (SPCAs) whose entry sites into the eye were displaced toward the temporal edge of the posterior staphyloma in 50 eyes. In 36 of the 662 eyes (5.4%), cross sections of the blood vessels were seen coursing through the scleral layer. In 177 of these 443 eyes, the retrobulbar posterior ciliary arteries (PCAs) also were observed as a cluster of circular or curved hyporeflectant structures just posterior to the sclera. CONCLUSIONS. Swept-source OCT is a high-quality method to detect intrascleral and retroscleral blood vessels in the eyes with pathologic myopia. These findings and longitudinal studies of these vessels will help in investigating how they are altered in pathologic myopia, and how such alterations are related to the complications in the retina-choroid and optic nerve.
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U2 - 10.1167/iovs.12-10371
DO - 10.1167/iovs.12-10371
M3 - Article
C2 - 23033385
AN - SCOPUS:84872041634
VL - 53
SP - 7290
EP - 7298
JO - Investigative Ophthalmology and Visual Science
JF - Investigative Ophthalmology and Visual Science
SN - 0146-0404
IS - 11
ER -