Oesophageal squamous cell carcinoma with lymphoid stroma - A case report

Masaki Mori, Hiroyuki Matsuda, Hiroyuki Kuwano, Hiroshi Matsuura, Keizo Sugimachi

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We treated a 70-year-old Japanese man with squamous cell carcinoma of the oesophagus with evidence of lymphoid stroma. The tumour consisted of a main lesion invading the muscular layer of the oesophagus, in association with wide areas of carcinoma in situ. The tumour stroma of the lesion was nondesmoplastic and was uniformly infiltrated mainly by abundant lymphocytes and plasma cells. Immunohistochemically, the lymphocytes consisted of a large number of T lymphocytes and a small number of B lymphocytes. S-100 protein positive cells were marked in the tumour cell nests and necrotic change of tumour cells was frequent. Abundant infiltration of lymphocytes and plasma cells was also wide-spread beneath the carcinoma in situ, together with the lymphoid follicles. Carcinoma with lymphoid stroma can occur not only in the breast, uterine cervix, nasopharynx and stomach but also in the oesophagus.

Original languageEnglish
Pages (from-to)473-479
Number of pages7
JournalVirchows Archiv A Pathological Anatomy and Histopathology
Volume415
Issue number5
DOIs
Publication statusPublished - Sep 1 1989

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Esophagus
Carcinoma in Situ
Lymphocytes
Plasma Cells
Neoplasms
Nasopharynx
S100 Proteins
Cervix Uteri
Squamous Cell Carcinoma
Stomach
Breast
B-Lymphocytes
Carcinoma
T-Lymphocytes
Esophageal Squamous Cell Carcinoma

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Cite this

Oesophageal squamous cell carcinoma with lymphoid stroma - A case report. / Mori, Masaki; Matsuda, Hiroyuki; Kuwano, Hiroyuki; Matsuura, Hiroshi; Sugimachi, Keizo.

In: Virchows Archiv A Pathological Anatomy and Histopathology, Vol. 415, No. 5, 01.09.1989, p. 473-479.

Research output: Contribution to journalArticle

Mori, Masaki ; Matsuda, Hiroyuki ; Kuwano, Hiroyuki ; Matsuura, Hiroshi ; Sugimachi, Keizo. / Oesophageal squamous cell carcinoma with lymphoid stroma - A case report. In: Virchows Archiv A Pathological Anatomy and Histopathology. 1989 ; Vol. 415, No. 5. pp. 473-479.
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