Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor

Yuhui Huang, Mami Sumida, Motofumi Kumazoe, Kaori Sugihara, Yumi Suemasu, Shuhei Yamada, Shuya Yamashita, Jyunichi Miyakawa, Takashi Takahashi, Hiroshi Tanaka, Yoshinori Fujimura, Hirofumi Tachibana

Research output: Contribution to journal › Article

11 Citations (Scopus)

Abstract

Green tea polyphenol (−)-epigallocatechin-3-O-gallate (EGCG) has been attributed to the activation of its cell surface sensing receptor 67 kDa laminin receptor (67LR). However, the action of EGCG to activate 67LR remains unknown. Here we show that EGCG undergoes oligomer formation on its surface receptor 67LR.

Original languageEnglish
Pages (from-to)1941-1944
Number of pages4
JournalChemical Communications
Volume53
Issue number12
DOIs
Publication statusPublished - 2017

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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    Huang, Y., Sumida, M., Kumazoe, M., Sugihara, K., Suemasu, Y., Yamada, S., Yamashita, S., Miyakawa, J., Takahashi, T., Tanaka, H., Fujimura, Y., & Tachibana, H. (2017). Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor. Chemical Communications, 53(12), 1941-1944. https://doi.org/10.1039/c6cc09504f