Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor

Yuhui Huang, Mami Sumida, Motofumi Kumazoe, Kaori Sugihara, Yumi Suemasu, Shuhei Yamada, Shuya Yamashita, Jyunichi Miyakawa, Takashi Takahashi, Hiroshi Tanaka, Yoshinori Fujimura, Hirofumi Tachibana

Research output: Contribution to journalArticle

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Abstract

Green tea polyphenol (−)-epigallocatechin-3-O-gallate (EGCG) has been attributed to the activation of its cell surface sensing receptor 67 kDa laminin receptor (67LR). However, the action of EGCG to activate 67LR remains unknown. Here we show that EGCG undergoes oligomer formation on its surface receptor 67LR.

Original languageEnglish
Pages (from-to)1941-1944
Number of pages4
JournalChemical Communications
Volume53
Issue number12
DOIs
Publication statusPublished - Jan 1 2017

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Laminin Receptors
Polyphenols
Oligomers
Molecules
Chemical activation
Tea
epigallocatechin gallate

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor. / Huang, Yuhui; Sumida, Mami; Kumazoe, Motofumi; Sugihara, Kaori; Suemasu, Yumi; Yamada, Shuhei; Yamashita, Shuya; Miyakawa, Jyunichi; Takahashi, Takashi; Tanaka, Hiroshi; Fujimura, Yoshinori; Tachibana, Hirofumi.

In: Chemical Communications, Vol. 53, No. 12, 01.01.2017, p. 1941-1944.

Research output: Contribution to journalArticle

Huang, Y, Sumida, M, Kumazoe, M, Sugihara, K, Suemasu, Y, Yamada, S, Yamashita, S, Miyakawa, J, Takahashi, T, Tanaka, H, Fujimura, Y & Tachibana, H 2017, 'Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor', Chemical Communications, vol. 53, no. 12, pp. 1941-1944. https://doi.org/10.1039/c6cc09504f
Huang Y, Sumida M, Kumazoe M, Sugihara K, Suemasu Y, Yamada S et al. Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor. Chemical Communications. 2017 Jan 1;53(12):1941-1944. https://doi.org/10.1039/c6cc09504f
Huang, Yuhui ; Sumida, Mami ; Kumazoe, Motofumi ; Sugihara, Kaori ; Suemasu, Yumi ; Yamada, Shuhei ; Yamashita, Shuya ; Miyakawa, Jyunichi ; Takahashi, Takashi ; Tanaka, Hiroshi ; Fujimura, Yoshinori ; Tachibana, Hirofumi. / Oligomer formation of a tea polyphenol, EGCG, on its sensing molecule 67 kDa laminin receptor. In: Chemical Communications. 2017 ; Vol. 53, No. 12. pp. 1941-1944.
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