On-chip cell transportation based on vibration-induced local flow in open chip environment

Takeshi Hayakawa, Shinya Sakuma, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

We present a novel cell manipulation method based on vibration-induced flow in open-chip environment. By applying circular vibration to a chip having micropillar patterns on its surface, local whirling flow is induced around the micropillars. Therefore, by patterning micropillar array on a chip and applying the circular vibration to the chip, we can achieve cell transportation along the array in an open chip environment. We theoretically analyzed this phenomenon with a single micropillar, and experimentally evaluated behaviours of manipulated microbeads with two micropillars. We confirm there are different manipulation modes according to the pitch of micropillars. We designed the micropillar array for an oocyte transportation based on these evaluations. We succeeded in the transportation of oocytes with up to 35.6 μm/s and confirmed that the velocity can be changed by changing the frequency and amplitude of the applied vibration.

Original languageEnglish
Title of host publicationIROS Hamburg 2015 - Conference Digest
Subtitle of host publicationIEEE/RSJ International Conference on Intelligent Robots and Systems
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1409-1414
Number of pages6
ISBN (Electronic)9781479999941
DOIs
Publication statusPublished - Dec 11 2015
Externally publishedYes
EventIEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2015 - Hamburg, Germany
Duration: Sep 28 2015Oct 2 2015

Publication series

NameIEEE International Conference on Intelligent Robots and Systems
Volume2015-December
ISSN (Print)2153-0858
ISSN (Electronic)2153-0866

Other

OtherIEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2015
CountryGermany
CityHamburg
Period9/28/1510/2/15

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering
  • Software
  • Computer Vision and Pattern Recognition
  • Computer Science Applications

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