On-chip cellular force measurement by Direct-Outer-Drive mechanism

Tsubasa Kakio, Turan Bilal, Shinya Sakuma, Makoto Kaneko, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

This paper reports a novel on-chip cellular force measurement method of single cells using Direct-Outer-Drive mechanism (D-O-D mechanism). This D-O-D mechanism enables high speed (1 kHz), high power (1 kN) and high accurate manipulation (nanometer-order) of Robochip (Robot-integrated microfluidic chip) and mechanical property measurement of single cells. We succeeded in mechanical property measurement of single animal cells with size of ∼ 15 μm. Furthermore, by adopting flow systems of microfluidic chip, we can achieve a high-speed, high-precision, and high-throughput consecutive cellular force measurement of single flowing cells.

Original languageEnglish
Title of host publication2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013
PublisherIEEE Computer Society
ISBN (Print)9781479915293
DOIs
Publication statusPublished - 2013
Externally publishedYes
Event2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013 - Nagoya, Japan
Duration: Nov 10 2013Nov 13 2013

Publication series

Name2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013

Other

Other2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013
CountryJapan
CityNagoya
Period11/10/1311/13/13

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering

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