On-chip enucleation of oocyte by magnetically driven microtools with ultrasonic vibration

Masaya Hagiwara; Tomohiro Kawahara; Lin Feng; Yoko Yamanishi; Fumihito Arai

doi:10.1109/ICRA.2011.5979930

On-chip enucleation of oocyte by magnetically driven microtools with ultrasonic vibration

Masaya Hagiwara, Tomohiro Kawahara, Lin Feng, Yoko Yamanishi, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

This paper describes an innovative driving method for magnetically driven microtools (MMT). 1.1 μm positioning accuracy of the MMT was obtained by applying a piezoelectric ceramic, which induced nanoscale vibration to the microfluidic chip, and reducing the friction on the MMT. Using this drive method, the enucleation process was conducted by dual-arm MMT. Permanent magnets are used to supply the driving power to the MMT allowing sufficient positioning accuracy to cut oocytes precisely. The nucleus was cut within 10 s, and the removed area was less than 25% of the original oocyte.

Original language	English
Title of host publication	2011 IEEE International Conference on Robotics and Automation, ICRA 2011
Pages	2680-2685
Number of pages	6
DOIs	https://doi.org/10.1109/ICRA.2011.5979930
Publication status	Published - 2011
Externally published	Yes
Event	2011 IEEE International Conference on Robotics and Automation, ICRA 2011 - Shanghai, China Duration: May 9 2011 → May 13 2011

Other

Other	2011 IEEE International Conference on Robotics and Automation, ICRA 2011
Country/Territory	China
City	Shanghai
Period	5/9/11 → 5/13/11

All Science Journal Classification (ASJC) codes

Software
Artificial Intelligence
Control and Systems Engineering
Electrical and Electronic Engineering

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10.1109/ICRA.2011.5979930

Cite this

Hagiwara, M, Kawahara, T, Feng, L, Yamanishi, Y & Arai, F 2011, On-chip enucleation of oocyte by magnetically driven microtools with ultrasonic vibration. in 2011 IEEE International Conference on Robotics and Automation, ICRA 2011., 5979930, pp. 2680-2685, 2011 IEEE International Conference on Robotics and Automation, ICRA 2011, Shanghai, China, 5/9/11. https://doi.org/10.1109/ICRA.2011.5979930

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year = "2011",

doi = "10.1109/ICRA.2011.5979930",

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AB - This paper describes an innovative driving method for magnetically driven microtools (MMT). 1.1 μm positioning accuracy of the MMT was obtained by applying a piezoelectric ceramic, which induced nanoscale vibration to the microfluidic chip, and reducing the friction on the MMT. Using this drive method, the enucleation process was conducted by dual-arm MMT. Permanent magnets are used to supply the driving power to the MMT allowing sufficient positioning accuracy to cut oocytes precisely. The nucleus was cut within 10 s, and the removed area was less than 25% of the original oocyte.

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ER -

On-chip enucleation of oocyte by magnetically driven microtools with ultrasonic vibration

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