On-chip high-speed and on-demand single microbeads loading

L. Feng, U. Huseyin, T. Kawahara, M. Hagiwara, Y. Yamanish, F. Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper presents on-demand microbeads delivery system in a microfluidic chip by magnetically driven microtool (MMT). The four of horizontally arranged permanent magnets and the piezoelectric vibrator are used to actuate the Ni based microtool precisely in the chip. The MMT injects the beads mechanically to flow and then into ejection operation part. We succeeded in transferring microbeads one by one with the required pace to the next process in order to achieve stable dispensing microbeads out from the microfluidic chip to incubation environment. We succeeded in demonstration of the delivery and ejection of polystyrene beads (100 μm) with the flow velocity of from 0.02 ml/h to 0.04 ml/h and MMT frequency from 1 Hz to 6 Hz to adjust the pitch of each micro-bead. The spacing interval of microbeads could be mainly adjusted by changing of MMT frequency and the flow velocity of output stream. The proposed system shows advantages of high-speed, high success ratio and disposable of microfluidic chip having MMT.

Original languageEnglish
Title of host publication2011 Int. Symp. on Micro-NanoMechatronics and Human Science, Symp. on "COE for Education and Research of Micro-Nano Mechatronics", Symposium on "Hyper Bio Assembler for 3D Cellular System Innovation"
PublisherIEEE Computer Society
Pages291-296
Number of pages6
ISBN (Print)9781457713613
DOIs
Publication statusPublished - 2011
Externally publishedYes
Event22nd Annual Symp. on Micro-Nano Mechatronics and Human Science, MHS 2011, Held Jointly with the Symp. on COE for Education and Research of Micro-Nano Mechatronics, Micro-Nano GCOE 2011, Symp. on Hyper Bio Assembler for 3D Cellular System Innovation - Nagoya, Japan
Duration: Nov 6 2011Nov 9 2011

Publication series

Name2011 Int. Symp. on Micro-NanoMechatronics and Human Science, Symp. on "COE for Education and Research of Micro-Nano Mechatronics", Symposium on "Hyper Bio Assembler for 3D Cellular System Innovation"

Other

Other22nd Annual Symp. on Micro-Nano Mechatronics and Human Science, MHS 2011, Held Jointly with the Symp. on COE for Education and Research of Micro-Nano Mechatronics, Micro-Nano GCOE 2011, Symp. on Hyper Bio Assembler for 3D Cellular System Innovation
Country/TerritoryJapan
CityNagoya
Period11/6/1111/9/11

All Science Journal Classification (ASJC) codes

  • Artificial Intelligence
  • Mechanical Engineering

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