On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure

Tomohiro Kawahara, Masakuni Sugita, Masaya Hagiwara, Yoko Yamanishi, Fumihito Arai, Hiroyuki Kawano, Ikuko Shihira-Ishikawa, Atsushi Miyawaki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

In this paper, we introduce an untethered type of magnetically driven microtool (MMT) with a force sensing function to investigate the stimulus characteristics of aquatic microorganisms in a microfluidic chip. The microchip is composed of the proposed MMTs, which have a Si-Ni hybrid structure, a transparent cover made of polydimethylsiloxane (PDMS), a glass substrate, and a microspacer to prevent both friction during the force measurement and damage to the micropattern of the MMT. The fabrication and drive performance of the MMT, which is actuated by permanent magnets from the outside of the microchip, verified in basic experiments. Finally, we succeeded in on-chip manipulation and sensing of microorganisms using this MMT, which we found to be easy to use.

Original languageEnglish
Title of host publication2012 IEEE International Conference on Robotics and Automation, ICRA 2012
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4112-4117
Number of pages6
ISBN (Print)9781467314039
DOIs
Publication statusPublished - Jan 1 2012
Externally publishedYes
Event 2012 IEEE International Conference on Robotics and Automation, ICRA 2012 - Saint Paul, MN, United States
Duration: May 14 2012May 18 2012

Other

Other 2012 IEEE International Conference on Robotics and Automation, ICRA 2012
CountryUnited States
CitySaint Paul, MN
Period5/14/125/18/12

Fingerprint

Microorganisms
Force measurement
Polydimethylsiloxane
Microfluidics
Permanent magnets
Friction
Fabrication
Glass
Substrates
Experiments

All Science Journal Classification (ASJC) codes

  • Software
  • Control and Systems Engineering
  • Artificial Intelligence
  • Electrical and Electronic Engineering

Cite this

Kawahara, T., Sugita, M., Hagiwara, M., Yamanishi, Y., Arai, F., Kawano, H., ... Miyawaki, A. (2012). On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure. In 2012 IEEE International Conference on Robotics and Automation, ICRA 2012 (pp. 4112-4117). [6224966] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ICRA.2012.6224966

On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure. / Kawahara, Tomohiro; Sugita, Masakuni; Hagiwara, Masaya; Yamanishi, Yoko; Arai, Fumihito; Kawano, Hiroyuki; Shihira-Ishikawa, Ikuko; Miyawaki, Atsushi.

2012 IEEE International Conference on Robotics and Automation, ICRA 2012. Institute of Electrical and Electronics Engineers Inc., 2012. p. 4112-4117 6224966.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kawahara, T, Sugita, M, Hagiwara, M, Yamanishi, Y, Arai, F, Kawano, H, Shihira-Ishikawa, I & Miyawaki, A 2012, On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure. in 2012 IEEE International Conference on Robotics and Automation, ICRA 2012., 6224966, Institute of Electrical and Electronics Engineers Inc., pp. 4112-4117, 2012 IEEE International Conference on Robotics and Automation, ICRA 2012, Saint Paul, MN, United States, 5/14/12. https://doi.org/10.1109/ICRA.2012.6224966
Kawahara T, Sugita M, Hagiwara M, Yamanishi Y, Arai F, Kawano H et al. On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure. In 2012 IEEE International Conference on Robotics and Automation, ICRA 2012. Institute of Electrical and Electronics Engineers Inc. 2012. p. 4112-4117. 6224966 https://doi.org/10.1109/ICRA.2012.6224966
Kawahara, Tomohiro ; Sugita, Masakuni ; Hagiwara, Masaya ; Yamanishi, Yoko ; Arai, Fumihito ; Kawano, Hiroyuki ; Shihira-Ishikawa, Ikuko ; Miyawaki, Atsushi. / On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure. 2012 IEEE International Conference on Robotics and Automation, ICRA 2012. Institute of Electrical and Electronics Engineers Inc., 2012. pp. 4112-4117
@inproceedings{968fe9aa65204e78902855cadb332607,
title = "On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure",
abstract = "In this paper, we introduce an untethered type of magnetically driven microtool (MMT) with a force sensing function to investigate the stimulus characteristics of aquatic microorganisms in a microfluidic chip. The microchip is composed of the proposed MMTs, which have a Si-Ni hybrid structure, a transparent cover made of polydimethylsiloxane (PDMS), a glass substrate, and a microspacer to prevent both friction during the force measurement and damage to the micropattern of the MMT. The fabrication and drive performance of the MMT, which is actuated by permanent magnets from the outside of the microchip, verified in basic experiments. Finally, we succeeded in on-chip manipulation and sensing of microorganisms using this MMT, which we found to be easy to use.",
author = "Tomohiro Kawahara and Masakuni Sugita and Masaya Hagiwara and Yoko Yamanishi and Fumihito Arai and Hiroyuki Kawano and Ikuko Shihira-Ishikawa and Atsushi Miyawaki",
year = "2012",
month = "1",
day = "1",
doi = "10.1109/ICRA.2012.6224966",
language = "English",
isbn = "9781467314039",
pages = "4112--4117",
booktitle = "2012 IEEE International Conference on Robotics and Automation, ICRA 2012",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
address = "United States",

}

TY - GEN

T1 - On-chip manipulation and sensing of microorganisms by magnetically driven microtools with a force sensing structure

AU - Kawahara, Tomohiro

AU - Sugita, Masakuni

AU - Hagiwara, Masaya

AU - Yamanishi, Yoko

AU - Arai, Fumihito

AU - Kawano, Hiroyuki

AU - Shihira-Ishikawa, Ikuko

AU - Miyawaki, Atsushi

PY - 2012/1/1

Y1 - 2012/1/1

N2 - In this paper, we introduce an untethered type of magnetically driven microtool (MMT) with a force sensing function to investigate the stimulus characteristics of aquatic microorganisms in a microfluidic chip. The microchip is composed of the proposed MMTs, which have a Si-Ni hybrid structure, a transparent cover made of polydimethylsiloxane (PDMS), a glass substrate, and a microspacer to prevent both friction during the force measurement and damage to the micropattern of the MMT. The fabrication and drive performance of the MMT, which is actuated by permanent magnets from the outside of the microchip, verified in basic experiments. Finally, we succeeded in on-chip manipulation and sensing of microorganisms using this MMT, which we found to be easy to use.

AB - In this paper, we introduce an untethered type of magnetically driven microtool (MMT) with a force sensing function to investigate the stimulus characteristics of aquatic microorganisms in a microfluidic chip. The microchip is composed of the proposed MMTs, which have a Si-Ni hybrid structure, a transparent cover made of polydimethylsiloxane (PDMS), a glass substrate, and a microspacer to prevent both friction during the force measurement and damage to the micropattern of the MMT. The fabrication and drive performance of the MMT, which is actuated by permanent magnets from the outside of the microchip, verified in basic experiments. Finally, we succeeded in on-chip manipulation and sensing of microorganisms using this MMT, which we found to be easy to use.

UR - http://www.scopus.com/inward/record.url?scp=84864489957&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84864489957&partnerID=8YFLogxK

U2 - 10.1109/ICRA.2012.6224966

DO - 10.1109/ICRA.2012.6224966

M3 - Conference contribution

SN - 9781467314039

SP - 4112

EP - 4117

BT - 2012 IEEE International Conference on Robotics and Automation, ICRA 2012

PB - Institute of Electrical and Electronics Engineers Inc.

ER -