ON-chip oocyte enucleation by robot integrated microfluidic chip

S. Sakuam, F. Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper presents on-chip enucleation of oocyte by the robot integrated microfluidic chip (Robochip). Enucleation process is mainly divided in three processes, which are (a) holding oocyte, (b) penetration to the oocyte, and (c) removal of the nucleus with cellular cytoplasm. Therefore, the robochip employed a pair of probe and a force sensor, and microneedle. Therefore, the Robochip contained an on-chip probe, an implanted force sensor, and an untethered microneedle in order to achieve the enucleation function. On-chip probe and the microneedle were driven by the external magnetic force in order to achieve a high output force to hold and penetrate an oocyte sufficiently. The on-chip enucleation was demonstrated and the high speed enucleation process with the zona pellucida was achieved.

Original languageEnglish
Title of host publicationIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Pages225-228
Number of pages4
DOIs
Publication statusPublished - 2013
Externally publishedYes
EventIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 - Taipei, Taiwan, Province of China
Duration: Jan 20 2013Jan 24 2013

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Other

OtherIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Country/TerritoryTaiwan, Province of China
CityTaipei
Period1/20/131/24/13

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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