On the role of ATP-gated P2X receptors in acute, inflammatory and neuropathic pain

Estelle Toulme; Tsuda Makoto; Baljit S. Khakh; Kazuhide Inoue

On the role of ATP-gated P2X receptors in acute, inflammatory and neuropathic pain

Estelle Toulme, Tsuda Makoto, Baljit S. Khakh, Kazuhide Inoue

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

P2X receptors are a family of ATP-gated cation channels with distinct functional properties and distributions in the body. In humans, P2X receptors comprise seven gene products that can form at least 14 known homo-and heterotrimeric receptors. In this chapter we focus on three P2X subunits (P2X3, P2X4, and P2X7) that each form homomeric receptors, and their roles in acute and chronic pain.

Original language	English
Title of host publication	Translational Pain Research
Subtitle of host publication	From Mouse to Man
Publisher	CRC Press
Pages	235-250
Number of pages	16
ISBN (Electronic)	9781439812105
ISBN (Print)	9781138116047
Publication status	Published - Jan 1 2009

All Science Journal Classification (ASJC) codes

Health Professions(all)
Medicine(all)
Biochemistry, Genetics and Molecular Biology(all)
Neuroscience(all)

Cite this

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On the role of ATP-gated P2X receptors in acute, inflammatory and neuropathic pain

Abstract

All Science Journal Classification (ASJC) codes

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