On the role of ATP-gated P2X receptors in acute, inflammatory and neuropathic pain

Estelle Toulme, Tsuda Makoto, Baljit S. Khakh, Kazuhide Inoue

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

P2X receptors are a family of ATP-gated cation channels with distinct functional properties and distributions in the body. In humans, P2X receptors comprise seven gene products that can form at least 14 known homo-and heterotrimeric receptors. In this chapter we focus on three P2X subunits (P2X3, P2X4, and P2X7) that each form homomeric receptors, and their roles in acute and chronic pain.

Original languageEnglish
Title of host publicationTranslational Pain Research
Subtitle of host publicationFrom Mouse to Man
PublisherCRC Press
Pages235-250
Number of pages16
ISBN (Electronic)9781439812105
ISBN (Print)9781138116047
Publication statusPublished - Jan 1 2009

All Science Journal Classification (ASJC) codes

  • Health Professions(all)
  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Neuroscience(all)

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