P2X receptors are a family of ATP-gated cation channels with distinct functional properties and distributions in the body. In humans, P2X receptors comprise seven gene products that can form at least 14 known homo-and heterotrimeric receptors. In this chapter we focus on three P2X subunits (P2X3, P2X4, and P2X7) that each form homomeric receptors, and their roles in acute and chronic pain.
|Title of host publication||Translational Pain Research|
|Subtitle of host publication||From Mouse to Man|
|Number of pages||16|
|Publication status||Published - Jan 1 2009|
All Science Journal Classification (ASJC) codes
- Health Professions(all)
- Biochemistry, Genetics and Molecular Biology(all)