One-Pot synthesis of indoles and aniline derivatives from nitroarenes under hydrogénation condition with supported gold nanoparticles

Yoshihiro Yamane, Xiaohao Liu, Akiyuki Hamasaki, Tamao Ishida, Masatake Haruta, Takushi Yokoyama, Makoto Tokunaga

Research output: Contribution to journalArticlepeer-review

129 Citations (Scopus)

Abstract

One-pot sequences of hydrogenation/hydroamination to form indoles from (2-nitroaryl)alkynes and hydrogenation/reductive amination to form aniline derivatives from nitroarenes and aldehydes were catalyzed by Au nanoparticles supported on Fe2O3. Nitro group selective hydrogenations and successive reactions were efficiently catalyzed under the conditions.

Original languageEnglish
Pages (from-to)5162-5165
Number of pages4
JournalOrganic Letters
Volume11
Issue number22
DOIs
Publication statusPublished - Dec 3 2009

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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