One-Pot synthesis of indoles and aniline derivatives from nitroarenes under hydrogénation condition with supported gold nanoparticles

Yoshihiro Yamane; Xiaohao Liu; Akiyuki Hamasaki; Tamao Ishida; Masatake Haruta; Takushi Yokoyama; Makoto Tokunaga

doi:10.1021/ol902061j

One-Pot synthesis of indoles and aniline derivatives from nitroarenes under hydrogénation condition with supported gold nanoparticles

Yoshihiro Yamane, Xiaohao Liu, Akiyuki Hamasaki, Tamao Ishida, Masatake Haruta, Takushi Yokoyama, Makoto Tokunaga

Research output: Contribution to journal › Article › peer-review

129 Citations (Scopus)

Abstract

One-pot sequences of hydrogenation/hydroamination to form indoles from (2-nitroaryl)alkynes and hydrogenation/reductive amination to form aniline derivatives from nitroarenes and aldehydes were catalyzed by Au nanoparticles supported on Fe₂O₃. Nitro group selective hydrogenations and successive reactions were efficiently catalyzed under the conditions.

Original language	English
Pages (from-to)	5162-5165
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	22
DOIs	https://doi.org/10.1021/ol902061j
Publication status	Published - Dec 3 2009

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol902061j

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One-Pot synthesis of indoles and aniline derivatives from nitroarenes under hydrogénation condition with supported gold nanoparticles. / Yamane, Yoshihiro; Liu, Xiaohao; Hamasaki, Akiyuki; Ishida, Tamao; Haruta, Masatake; Yokoyama, Takushi; Tokunaga, Makoto.

In: Organic Letters, Vol. 11, No. 22, 03.12.2009, p. 5162-5165.

Research output: Contribution to journal › Article › peer-review

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AU - Haruta, Masatake

AU - Yokoyama, Takushi

AU - Tokunaga, Makoto

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