Ontogeny of circadian clock gene expression in the pineal and the suprachiasmatic nucleus of chick embryo

Naritoshi Okabayashi, Shinobu Yasuo, Miwa Watanabe, Takao Namikawa, Shizufumi Ebihara, Takashi Yoshimura

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Avian circadian rhythms are regulated by a multiple oscillatory system consisting of the pineal, the suprachiasmatic nucleus (SCN) and the eye. In the present study, ontogeny of circadian clock in the pineal and the SCN of chick embryo was examined using Per2 expression as a marker. A daily rhythmicity of Per2 expression was first detectable at embryonic day (ED) 18 in the pineal and at ED 16 in the SCN under light-dark (LD) cycles. The amplitude of the rhythmicity increased during the development. In contrast, little expression was observed during the development in constant darkness. These results suggest that although circadian clock matures by the end of the embryonic life in chicken, LD cycles are required for the expression of the Per2.

Original languageEnglish
Pages (from-to)231-234
Number of pages4
JournalBrain Research
Volume990
Issue number1-2
DOIs
Publication statusPublished - Nov 14 2003
Externally publishedYes

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Circadian Clocks
Suprachiasmatic Nucleus
Chick Embryo
Photoperiod
Periodicity
Gene Expression
Darkness
Circadian Rhythm
Chickens

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Cite this

Ontogeny of circadian clock gene expression in the pineal and the suprachiasmatic nucleus of chick embryo. / Okabayashi, Naritoshi; Yasuo, Shinobu; Watanabe, Miwa; Namikawa, Takao; Ebihara, Shizufumi; Yoshimura, Takashi.

In: Brain Research, Vol. 990, No. 1-2, 14.11.2003, p. 231-234.

Research output: Contribution to journalArticle

Okabayashi, Naritoshi ; Yasuo, Shinobu ; Watanabe, Miwa ; Namikawa, Takao ; Ebihara, Shizufumi ; Yoshimura, Takashi. / Ontogeny of circadian clock gene expression in the pineal and the suprachiasmatic nucleus of chick embryo. In: Brain Research. 2003 ; Vol. 990, No. 1-2. pp. 231-234.
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