Oocyte mechanical caractrization by robot integrated microfluidic chip for high-throughput quality evaluation

Shinya Sakuma, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We presents a mechanical characterization of oocyte for high-throughput quality evaluation. In order to achieve the biomedical disposable applications, our characterization system consists of only four parts: a sensing part, an actuation part, a flow-control part, and a robot integrated microfiuidic chip (Robochip) as a disposable part. Robochip has advantages of both of micromechanical manipulator and Lab-on-a-Chip devices, which are, briefly, high-accuracy with high-output-force and high-throughput abilities. Robochip contains a pair of a width-tunable-wall and a force sensor. The mechanical characterization was based on the stress relaxation phenomena. The analytical model of the oocyte was expressed using Maxwell model, we assumed the shape of the deformation follows the Hertz's contact theory. The mechanical characterization was demonstrated, and the results shows that the elastic and viscoelastic characters were measured. Moreover, experimental and simulated values are good agreement.

Original languageEnglish
Title of host publication17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PublisherChemical and Biological Microsystems Society
Pages1683-1685
Number of pages3
ISBN (Print)9781632666246
Publication statusPublished - 2013
Externally publishedYes
Event17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
Duration: Oct 27 2013Oct 31 2013

Publication series

Name17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Volume3

Other

Other17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
CountryGermany
CityFreiburg
Period10/27/1310/31/13

All Science Journal Classification (ASJC) codes

  • Bioengineering

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