Oogenesis in vitro

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Reconstitution of oogenesis in vitro provides a useful tool for improving our understanding of oogenesis and also an alternative source of oocytes for reproduction. In mice, it has become possible to produce fully mature oocytes from pluripotent stem cells (PSCs) in culture. The PSC-derived oocytes fertilized with wild-type sperm are capable of giving rise to pups that grow to fertile adult mice. This section describes how to reconstitute oogenesis in vitro including technical backgrounds, similarity and difference between in vivo and in vitro oogenesis, and a current situation of the application to humans.

Original languageEnglish
Title of host publicationEncyclopedia of Reproduction
PublisherElsevier
Pages225-231
Number of pages7
ISBN (Electronic)9780128151457
DOIs
Publication statusPublished - Jan 1 2018

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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