Opinion to

Design, synthesis, antimicrobial, and antioxidant activities of novel {4,5-(substituted diphenyl)-4H-1,2,4-triazol-3-ylthio}acetyl chloride

Khamid U. Khodjaniyazov, Kohei Torikai

Research output: Contribution to journalArticle

Abstract

To discover novel triazole-based antimicrobial agents, design and synthesis of acid chlorides possessing a 1,2,4-triazole core was reported in this journal in 2018. However, we found that the reported spectroscopic data did not show any agreement with the proposed acid chloride structure. Herein, we described our opinion, which was supported by IR data, circumstantial evidences, and mechanistic insight, that the products obtained in the topical paper would be thioesters.

Original languageEnglish
Pages (from-to)817-821
Number of pages5
JournalWalailak Journal of Science and Technology
Volume16
Issue number11
Publication statusPublished - Jan 1 2019

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Chlorides
Antioxidants
Acids
Triazoles
Anti-Infective Agents
acetyl chloride
diphenyl
1,2,4-triazole

All Science Journal Classification (ASJC) codes

  • General

Cite this

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abstract = "To discover novel triazole-based antimicrobial agents, design and synthesis of acid chlorides possessing a 1,2,4-triazole core was reported in this journal in 2018. However, we found that the reported spectroscopic data did not show any agreement with the proposed acid chloride structure. Herein, we described our opinion, which was supported by IR data, circumstantial evidences, and mechanistic insight, that the products obtained in the topical paper would be thioesters.",
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