Optical coherence tomography angiography for detecting choroidal neovascularization secondary to punctate inner choroidopathy

Shintaro Nakao, Yoshihiro Kaizu, Yuji Oshima, Taiji Sakamoto, Tatsuro Ishibashi, Koh Hei Sonoda

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Punctate inner choroidopathy (PIC) is a relatively uncommon inflammatory multifocal cho-rioretinopathy that predominantly affects young, myopic women. Subfoveal choroidal neovascularization (CNV) often leads to rapid loss of sight. Fluorescein angiography (FA) and indocyanine green angiography (ICGA) remain the existing gold standards for CNV diagnosis. However, these methods are invasive and time-consuming. Recently, optical coherence tomography angiography (OCTA) has been used more frequently as an adjunct to FA/ICGA. In this report, a 38-year-old woman with PIC and idiopathic CNV presented with blurred vision despite 18/20 visual acuity. FA revealed positive staining and possible leakage, but did not provide clear evidence of CNV. OCTA detected abnormal flow in the outer retina, corresponding to type 2 CNV, that decreased following intravitreal anti-vascular endothelial growth factor (VEGF) therapy. Furthermore, OCTA could show remodeling of the choroidal capillaries after the treatment. OCTA may be helpful in the detection, follow-up, and evaluation of therapeutic strategies to treat CNV secondary to PIC.

Original languageEnglish
Pages (from-to)1157-1161
Number of pages5
JournalOphthalmic Surgery Lasers and Imaging Retina
Volume47
Issue number12
DOIs
Publication statusPublished - Dec 2016

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Choroidal Neovascularization
Optical Coherence Tomography
Angiography
Fluorescein Angiography
Indocyanine Green
Vascular Endothelial Growth Factor A
Visual Acuity
Retina
Therapeutics
Staining and Labeling

All Science Journal Classification (ASJC) codes

  • Surgery
  • Ophthalmology

Cite this

Optical coherence tomography angiography for detecting choroidal neovascularization secondary to punctate inner choroidopathy. / Nakao, Shintaro; Kaizu, Yoshihiro; Oshima, Yuji; Sakamoto, Taiji; Ishibashi, Tatsuro; Sonoda, Koh Hei.

In: Ophthalmic Surgery Lasers and Imaging Retina, Vol. 47, No. 12, 12.2016, p. 1157-1161.

Research output: Contribution to journalArticle

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