Optimization of fermentation conditions for high L-lactic acid production from cellobiose by Entercoccus mundtii QU 25

Impact of pH control and temperature on cell growth and changes in metabolites

Mohamed Ali Abdel-Rahman, Takeshi Zendo, Kenji Sonomoto, Yukihiro Tashiro

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Optimization of L-(+)-lactic acid production from cellobiose, one of the main cellulase inhibitors during saccharifaying process, was studied. Fermentation runs pH-controlled at 7.0 provided the highest lactic acid produced (18.6 g/L) and maximum lactic acid productivity (2.1 g/L/h) which were increased by 376% and 346%, respectively in comparison to non pH-controlled batches. Moreover, the maximum L-lactic acid yield and optical purity were obtained at pH 7.0 with 0.94 g/g and 100%, respectively. The optimum temperature was found to be 43°C, at which the lactic acid yield and maximum productivity were 1.0 g/g and 3.44 g/L/h, respectively. This study provides an encouraging means for economic production of optically pure L-lactic acid from pre-hydrolyzed cellulosic materials.

Original languageEnglish
Title of host publicationICEEA 2010 - 2010 International Conference on Environmental Engineering and Applications, Proceedings
Pages307-311
Number of pages5
DOIs
Publication statusPublished - 2010
Event2010 International Conference on Environmental Engineering and Applications, ICEEA 2010 - Singapore, Singapore
Duration: Sep 10 2010Sep 12 2010

Other

Other2010 International Conference on Environmental Engineering and Applications, ICEEA 2010
CountrySingapore
CitySingapore
Period9/10/109/12/10

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Cell growth
Lactic acid
Metabolites
Fermentation
Temperature
Productivity
Economics

All Science Journal Classification (ASJC) codes

  • Environmental Engineering

Cite this

Optimization of fermentation conditions for high L-lactic acid production from cellobiose by Entercoccus mundtii QU 25 : Impact of pH control and temperature on cell growth and changes in metabolites. / Abdel-Rahman, Mohamed Ali; Zendo, Takeshi; Sonomoto, Kenji; Tashiro, Yukihiro.

ICEEA 2010 - 2010 International Conference on Environmental Engineering and Applications, Proceedings. 2010. p. 307-311 5596153.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abdel-Rahman, MA, Zendo, T, Sonomoto, K & Tashiro, Y 2010, Optimization of fermentation conditions for high L-lactic acid production from cellobiose by Entercoccus mundtii QU 25: Impact of pH control and temperature on cell growth and changes in metabolites. in ICEEA 2010 - 2010 International Conference on Environmental Engineering and Applications, Proceedings., 5596153, pp. 307-311, 2010 International Conference on Environmental Engineering and Applications, ICEEA 2010, Singapore, Singapore, 9/10/10. https://doi.org/10.1109/ICEEA.2010.5596153
Abdel-Rahman, Mohamed Ali ; Zendo, Takeshi ; Sonomoto, Kenji ; Tashiro, Yukihiro. / Optimization of fermentation conditions for high L-lactic acid production from cellobiose by Entercoccus mundtii QU 25 : Impact of pH control and temperature on cell growth and changes in metabolites. ICEEA 2010 - 2010 International Conference on Environmental Engineering and Applications, Proceedings. 2010. pp. 307-311
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