TY - JOUR
T1 - Optimization of magnetic nanoparticles for magnetic particle imaging
AU - Ludwig, Frank
AU - Wawrzik, Thilo
AU - Yoshida, Takashi
AU - Gehrke, Nicole
AU - Briel, Andreas
AU - Eberbeck, Dietmar
AU - Schilling, Meinhard
N1 - Funding Information:
Financial support from the DFG via SFB 578 and JSPS via Grant-in-Aid for Young Scientists (B) (23760369) are acknowledged.
PY - 2012
Y1 - 2012
N2 - Systematic studies of the magnetic properties of magnetic nanoparticles from FeraSpin R and the FeraSpin Series with respect to their suitability as tracers for magnetic particle imaging are presented. Magnetic particle spectroscopy measurements indicate that FeraSpin R exhibits a harmonic spectrum very similar to that of Resovist, whereas FeraSpin L, XL, and XXL show a 2.5-fold increase of harmonic amplitudes compared to FeraSpin R. To understand the differences between the various samples of the FeraSpin Series, representing size-selected, narrowly distributed particles of identical composition extracted from FeraSpin R, measurements of the ac susceptibility (ACS), magnetorelaxometry (MRX), and static M-H curves were performed on suspended and immobilized particle samples. ACS and MRX measurements on immobilized samples indicate a wide distribution of anisotropy energies despite the narrow distribution of hydrodynamic sizes. Static magnetization measurements show that all samples exhibit a bimodal distribution of magnetic moments: The fraction of larger moments corresponds to the contribution from the overall particle core, whereas the smaller is attributed to the contribution from the crystallites comprising the core.
AB - Systematic studies of the magnetic properties of magnetic nanoparticles from FeraSpin R and the FeraSpin Series with respect to their suitability as tracers for magnetic particle imaging are presented. Magnetic particle spectroscopy measurements indicate that FeraSpin R exhibits a harmonic spectrum very similar to that of Resovist, whereas FeraSpin L, XL, and XXL show a 2.5-fold increase of harmonic amplitudes compared to FeraSpin R. To understand the differences between the various samples of the FeraSpin Series, representing size-selected, narrowly distributed particles of identical composition extracted from FeraSpin R, measurements of the ac susceptibility (ACS), magnetorelaxometry (MRX), and static M-H curves were performed on suspended and immobilized particle samples. ACS and MRX measurements on immobilized samples indicate a wide distribution of anisotropy energies despite the narrow distribution of hydrodynamic sizes. Static magnetization measurements show that all samples exhibit a bimodal distribution of magnetic moments: The fraction of larger moments corresponds to the contribution from the overall particle core, whereas the smaller is attributed to the contribution from the crystallites comprising the core.
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U2 - 10.1109/TMAG.2012.2197601
DO - 10.1109/TMAG.2012.2197601
M3 - Article
AN - SCOPUS:84867833950
SN - 0018-9464
VL - 48
SP - 3780
EP - 3783
JO - IEEE Transactions on Magnetics
JF - IEEE Transactions on Magnetics
IS - 11
M1 - 6332841
ER -