Optimization of the Electrospraying Parameters for Formulation of Biopolymeric Microcapsules

Joshua Anani, H. Noby, Abdelrahman Zkria, Tsuyoshi Yoshitake, Marwa Elkady

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

There has been a surge in applying alginate microcapsules in diverse fields due to the numerous advantages of their non-toxicity, simple synthesis, and mechanical and chemical stability. Electrospraying is a simple and excellent technique for producing small microcapsules. This study aimed to analyze the trends in the operational parameters of the electrospraying technique, observed extreme conditions of the electrospraying, and selected the best performing parameters for producing small and spherical microcapsules. Alginate concentration was found to produce smaller microcapsules when kept at a minimum. However, the Implosion of microcapsules formed with less than 2%w/v alginate concentration was observed. Voltage increment produced smaller capsules, and fibre formation began at 21kV. Lower feed rates favoured both smaller microcapsules and better sphericity. Reduction in the needle orifice also favoured the formation of smaller microcapsules with less sphericity. Overall, a needle gauge of 27G, a voltage of 21kV, a flowrate of 0.5ml/h, and 2% w/v calcium chloride concentration were the best parameter combinations for producing small and spherical microcapsules.

Original languageEnglish
Title of host publicationMaterials Science Forum
PublisherTrans Tech Publications Ltd
Pages87-93
Number of pages7
DOIs
Publication statusPublished - 2022

Publication series

NameMaterials Science Forum
Volume1075
ISSN (Print)0255-5476
ISSN (Electronic)1662-9752

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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