Oral administration of chicken breast extract activates serotonin metabolism in the hippocampus of rats

Shozo Tomonaga, Mikako Sato, Yoshihisa Takahata, Fumiki Morimatsu, Mitsuhiro Furuse

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We previously reported that Chicken Breast Extract (CBEX) had an antidepressant-like effect in rats. In the present study to further clarify, the mechanism of action of CBEX, the effects of CBEX on the brain serotonin (5-HT) system was investigated mthe ventral hippocampus of rats, using an in vivo micro dialysis. 5-Hydroxyindoleacetic acid, a major metabolite of serotonin, was significantly increased in animals orally administered CBEX. This result indicates that CBEX may activate 5-HT metabolism in the brain. Since, a previous study indicated that orally administered CBEX increases levels of the putative neurotransmitter carnosine in the hippocampus, carnosine might be involved in the action of CBEX.

Original languageEnglish
Pages (from-to)2276-2279
Number of pages4
JournalJournal of Animal and Veterinary Advances
Volume8
Issue number11
Publication statusPublished - 2009

Fingerprint

hippocampus
serotonin
oral administration
breasts
Oral Administration
Chickens
Hippocampus
Serotonin
Breast
chickens
metabolism
rats
extracts
Carnosine
carnosine
5-hydroxyindoleacetic acid
brain
antidepressants
Hydroxyindoleacetic Acid
Brain

All Science Journal Classification (ASJC) codes

  • Agronomy and Crop Science
  • veterinary(all)

Cite this

Oral administration of chicken breast extract activates serotonin metabolism in the hippocampus of rats. / Tomonaga, Shozo; Sato, Mikako; Takahata, Yoshihisa; Morimatsu, Fumiki; Furuse, Mitsuhiro.

In: Journal of Animal and Veterinary Advances, Vol. 8, No. 11, 2009, p. 2276-2279.

Research output: Contribution to journalArticle

Tomonaga, Shozo ; Sato, Mikako ; Takahata, Yoshihisa ; Morimatsu, Fumiki ; Furuse, Mitsuhiro. / Oral administration of chicken breast extract activates serotonin metabolism in the hippocampus of rats. In: Journal of Animal and Veterinary Advances. 2009 ; Vol. 8, No. 11. pp. 2276-2279.
@article{57660c7d801c496695c53f23fd3e0379,
title = "Oral administration of chicken breast extract activates serotonin metabolism in the hippocampus of rats",
abstract = "We previously reported that Chicken Breast Extract (CBEX) had an antidepressant-like effect in rats. In the present study to further clarify, the mechanism of action of CBEX, the effects of CBEX on the brain serotonin (5-HT) system was investigated mthe ventral hippocampus of rats, using an in vivo micro dialysis. 5-Hydroxyindoleacetic acid, a major metabolite of serotonin, was significantly increased in animals orally administered CBEX. This result indicates that CBEX may activate 5-HT metabolism in the brain. Since, a previous study indicated that orally administered CBEX increases levels of the putative neurotransmitter carnosine in the hippocampus, carnosine might be involved in the action of CBEX.",
author = "Shozo Tomonaga and Mikako Sato and Yoshihisa Takahata and Fumiki Morimatsu and Mitsuhiro Furuse",
year = "2009",
language = "English",
volume = "8",
pages = "2276--2279",
journal = "Journal of Animal and Veterinary Advances",
issn = "1680-5593",
publisher = "Medwell Publishing",
number = "11",

}

TY - JOUR

T1 - Oral administration of chicken breast extract activates serotonin metabolism in the hippocampus of rats

AU - Tomonaga, Shozo

AU - Sato, Mikako

AU - Takahata, Yoshihisa

AU - Morimatsu, Fumiki

AU - Furuse, Mitsuhiro

PY - 2009

Y1 - 2009

N2 - We previously reported that Chicken Breast Extract (CBEX) had an antidepressant-like effect in rats. In the present study to further clarify, the mechanism of action of CBEX, the effects of CBEX on the brain serotonin (5-HT) system was investigated mthe ventral hippocampus of rats, using an in vivo micro dialysis. 5-Hydroxyindoleacetic acid, a major metabolite of serotonin, was significantly increased in animals orally administered CBEX. This result indicates that CBEX may activate 5-HT metabolism in the brain. Since, a previous study indicated that orally administered CBEX increases levels of the putative neurotransmitter carnosine in the hippocampus, carnosine might be involved in the action of CBEX.

AB - We previously reported that Chicken Breast Extract (CBEX) had an antidepressant-like effect in rats. In the present study to further clarify, the mechanism of action of CBEX, the effects of CBEX on the brain serotonin (5-HT) system was investigated mthe ventral hippocampus of rats, using an in vivo micro dialysis. 5-Hydroxyindoleacetic acid, a major metabolite of serotonin, was significantly increased in animals orally administered CBEX. This result indicates that CBEX may activate 5-HT metabolism in the brain. Since, a previous study indicated that orally administered CBEX increases levels of the putative neurotransmitter carnosine in the hippocampus, carnosine might be involved in the action of CBEX.

UR - http://www.scopus.com/inward/record.url?scp=77951639235&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77951639235&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:77951639235

VL - 8

SP - 2276

EP - 2279

JO - Journal of Animal and Veterinary Advances

JF - Journal of Animal and Veterinary Advances

SN - 1680-5593

IS - 11

ER -