TY - JOUR
T1 - Oral administration of hot water extracts of Chlorella vulgaris reduces IgE production against milk casein in mice
AU - Hasegawa, T.
AU - Ito, K.
AU - Ueno, S.
AU - Kumamoto, S.
AU - Ando, Y.
AU - Yamada, A.
AU - Nomoto, K.
AU - Yasunobu, Y.
N1 - Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 1999/5
Y1 - 1999/5
N2 - Hot water extract of Chlorella vulgaris (CVE) is a biological response modifier (BRM) which enhances resistance to Listeria monocytogenes through augmentation of helper T cell type 1 (Th1) responses producing gamma-interferon (γIFN). We show here that oral administration of CVE in mice suppressed the production of immunoglobulin (Ig)E against casein antigen accompanied by increased γIFN and IL-12 mRNA expression. Oral administration of CVE enhanced Th1 response to casein in the spleen of casein immunized mice. CVE may be useful for prevention of allergic diseases with a predominant Th2 response. Copyright (C) 1999 International Society for Immunopharmacology.
AB - Hot water extract of Chlorella vulgaris (CVE) is a biological response modifier (BRM) which enhances resistance to Listeria monocytogenes through augmentation of helper T cell type 1 (Th1) responses producing gamma-interferon (γIFN). We show here that oral administration of CVE in mice suppressed the production of immunoglobulin (Ig)E against casein antigen accompanied by increased γIFN and IL-12 mRNA expression. Oral administration of CVE enhanced Th1 response to casein in the spleen of casein immunized mice. CVE may be useful for prevention of allergic diseases with a predominant Th2 response. Copyright (C) 1999 International Society for Immunopharmacology.
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U2 - 10.1016/S0192-0561(99)00013-2
DO - 10.1016/S0192-0561(99)00013-2
M3 - Article
C2 - 10408628
AN - SCOPUS:0033031387
SN - 1567-5769
VL - 21
SP - 311
EP - 323
JO - International Immunopharmacology
JF - International Immunopharmacology
IS - 5
ER -