Orthopedic management of skeletal metastases

Nokitaka Setsu, Eisuke Kobayashi, Akira Kawai

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Recent advances in drug therapy for metastatic bone diseases are changing the indications for surgical treatments. Bone-modifying agents, including bisphosphonates and denosumab, have reduced skeletal-related events. Meanwhile, novel anticancer drugs that have been developed, especially molecular-targeted drugs, can improve the prognoses of patients with bone metastases, thereby potentially increasing the number of patients who could receive benefits from surgeries for metastases. A multidisciplinary approach and the early involvement of surgeons are required for the application of adequate orthopedic treatments, including braces, rehabilitation, and surgeries for local tumor control, palliative fixation, and spinal decompression.

Original languageEnglish
Pages (from-to)1350-1354
Number of pages5
JournalJapanese Journal of Cancer and Chemotherapy
Volume42
Issue number11
Publication statusPublished - Nov 1 2015
Externally publishedYes

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Orthopedics
Neoplasm Metastasis
Bone and Bones
Braces
Bone Diseases
Diphosphonates
Decompression
Pharmaceutical Preparations
Rehabilitation
Drug Therapy
Therapeutics
Neoplasms
Surgeons
Denosumab

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Orthopedic management of skeletal metastases. / Setsu, Nokitaka; Kobayashi, Eisuke; Kawai, Akira.

In: Japanese Journal of Cancer and Chemotherapy, Vol. 42, No. 11, 01.11.2015, p. 1350-1354.

Research output: Contribution to journalArticle

Setsu, N, Kobayashi, E & Kawai, A 2015, 'Orthopedic management of skeletal metastases', Japanese Journal of Cancer and Chemotherapy, vol. 42, no. 11, pp. 1350-1354.
Setsu, Nokitaka ; Kobayashi, Eisuke ; Kawai, Akira. / Orthopedic management of skeletal metastases. In: Japanese Journal of Cancer and Chemotherapy. 2015 ; Vol. 42, No. 11. pp. 1350-1354.
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