Osteoclastogenesis inhibitory effect of ergosterol peroxide isolated from Pleurotus eryngii

Satoru Yokoyama, Tran Hai Bang, Kuniyoshi Shimizu, Ryuichiro Kondo

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Ergosterol peroxide was isolated from the ethanol extract of Pleurotus eryngii as an inhibitor of osteoclast differentiation. This compound showed an inhibitory effect in a dose-dependent manner and an inhibition rate of up to 62% with low cytotoxicity, even at a concentration as low as 1.0 μg/mL.

Original languageEnglish
Pages (from-to)1163-1164
Number of pages2
JournalNatural product communications
Volume7
Issue number9
DOIs
Publication statusPublished - 2012

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine

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