Osteoclastogenesis inhibitory effect of ergosterol peroxide isolated from Pleurotus eryngii

Satoru Yokoyama, Tran Hai Bang, Kuniyoshi Shimizu, Ryuichiro Kondo

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Ergosterol peroxide was isolated from the ethanol extract of Pleurotus eryngii as an inhibitor of osteoclast differentiation. This compound showed an inhibitory effect in a dose-dependent manner and an inhibition rate of up to 62% with low cytotoxicity, even at a concentration as low as 1.0 μg/mL.

Original languageEnglish
Pages (from-to)1163-1164
Number of pages2
JournalNatural Product Communications
Volume7
Issue number9
Publication statusPublished - Oct 2 2012

Fingerprint

Pleurotus eryngii
Pleurotus
osteoclasts
ergosterol
Osteoclasts
peroxides
Osteogenesis
cytotoxicity
Ethanol
ethanol
extracts
dosage
ergosterol-5,8-peroxide

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery
  • Plant Science
  • Complementary and alternative medicine

Cite this

Osteoclastogenesis inhibitory effect of ergosterol peroxide isolated from Pleurotus eryngii. / Yokoyama, Satoru; Bang, Tran Hai; Shimizu, Kuniyoshi; Kondo, Ryuichiro.

In: Natural Product Communications, Vol. 7, No. 9, 02.10.2012, p. 1163-1164.

Research output: Contribution to journalArticle

Yokoyama, Satoru ; Bang, Tran Hai ; Shimizu, Kuniyoshi ; Kondo, Ryuichiro. / Osteoclastogenesis inhibitory effect of ergosterol peroxide isolated from Pleurotus eryngii. In: Natural Product Communications. 2012 ; Vol. 7, No. 9. pp. 1163-1164.
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