Osteoconductivity and bioresorption of an interconnecting porous carbonate apatite with enhanced mechanical strength

Nguyen Xuan Thanh Tram, Michito Maruta, Kanji Tusru, Shigeki Matsuya, Kunio Ishikawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have established a processing method to fabricate three-dimensional porous carbonate apatite (CO3Ap) with interconnected porous structure and improved mechanical strength. Briefly, porous CO3Ap materials were produced via phosphorization of porous calcite precursor in hydrothermal condition. In order to make porous calcite precursor, negative replication of modified polyurethane foam template was conducted. In this study, an in vivo behavior of that porous CO3Ap was evaluated. The interconnected porous CO3Ap material was implanted in the tibia of Japanese male rabbits and removed after a period of 6 months. Micro-computed tomography (μ-CT) scanner and histological analysis were used to characterize the bone formation response of the porous CO3Ap. The results suggest that porous CO3Ap with enhanced mechanical strength was not only osteoconductive but also bioresorbable therefore it could be used as bone substitute material.

Original languageEnglish
Title of host publicationBioceramics 27
EditorsIka Dewi Ana, Kuwat Triyana
PublisherTrans Tech Publications Ltd
Pages23-26
Number of pages4
ISBN (Print)9783035710403
DOIs
Publication statusPublished - Jan 1 2016
Event27th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, 2015 - Bali, Indonesia
Duration: Oct 27 2015Oct 29 2015

Publication series

NameKey Engineering Materials
Volume696
ISSN (Print)1013-9826

Other

Other27th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, 2015
CountryIndonesia
CityBali
Period10/27/1510/29/15

Fingerprint

Calcium Carbonate
Calcite
Apatite
Strength of materials
Porous materials
Carbonates
Bone
Bone Substitutes
Polyurethanes
Tomography
Foams
Processing
carboapatite
polyurethane foam

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Tram, N. X. T., Maruta, M., Tusru, K., Matsuya, S., & Ishikawa, K. (2016). Osteoconductivity and bioresorption of an interconnecting porous carbonate apatite with enhanced mechanical strength. In I. D. Ana, & K. Triyana (Eds.), Bioceramics 27 (pp. 23-26). (Key Engineering Materials; Vol. 696). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/KEM.696.23

Osteoconductivity and bioresorption of an interconnecting porous carbonate apatite with enhanced mechanical strength. / Tram, Nguyen Xuan Thanh; Maruta, Michito; Tusru, Kanji; Matsuya, Shigeki; Ishikawa, Kunio.

Bioceramics 27. ed. / Ika Dewi Ana; Kuwat Triyana. Trans Tech Publications Ltd, 2016. p. 23-26 (Key Engineering Materials; Vol. 696).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tram, NXT, Maruta, M, Tusru, K, Matsuya, S & Ishikawa, K 2016, Osteoconductivity and bioresorption of an interconnecting porous carbonate apatite with enhanced mechanical strength. in ID Ana & K Triyana (eds), Bioceramics 27. Key Engineering Materials, vol. 696, Trans Tech Publications Ltd, pp. 23-26, 27th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, 2015, Bali, Indonesia, 10/27/15. https://doi.org/10.4028/www.scientific.net/KEM.696.23
Tram NXT, Maruta M, Tusru K, Matsuya S, Ishikawa K. Osteoconductivity and bioresorption of an interconnecting porous carbonate apatite with enhanced mechanical strength. In Ana ID, Triyana K, editors, Bioceramics 27. Trans Tech Publications Ltd. 2016. p. 23-26. (Key Engineering Materials). https://doi.org/10.4028/www.scientific.net/KEM.696.23
Tram, Nguyen Xuan Thanh ; Maruta, Michito ; Tusru, Kanji ; Matsuya, Shigeki ; Ishikawa, Kunio. / Osteoconductivity and bioresorption of an interconnecting porous carbonate apatite with enhanced mechanical strength. Bioceramics 27. editor / Ika Dewi Ana ; Kuwat Triyana. Trans Tech Publications Ltd, 2016. pp. 23-26 (Key Engineering Materials).
@inproceedings{39d3353398d4490989148b2e25334fc5,
title = "Osteoconductivity and bioresorption of an interconnecting porous carbonate apatite with enhanced mechanical strength",
abstract = "We have established a processing method to fabricate three-dimensional porous carbonate apatite (CO3Ap) with interconnected porous structure and improved mechanical strength. Briefly, porous CO3Ap materials were produced via phosphorization of porous calcite precursor in hydrothermal condition. In order to make porous calcite precursor, negative replication of modified polyurethane foam template was conducted. In this study, an in vivo behavior of that porous CO3Ap was evaluated. The interconnected porous CO3Ap material was implanted in the tibia of Japanese male rabbits and removed after a period of 6 months. Micro-computed tomography (μ-CT) scanner and histological analysis were used to characterize the bone formation response of the porous CO3Ap. The results suggest that porous CO3Ap with enhanced mechanical strength was not only osteoconductive but also bioresorbable therefore it could be used as bone substitute material.",
author = "Tram, {Nguyen Xuan Thanh} and Michito Maruta and Kanji Tusru and Shigeki Matsuya and Kunio Ishikawa",
year = "2016",
month = "1",
day = "1",
doi = "10.4028/www.scientific.net/KEM.696.23",
language = "English",
isbn = "9783035710403",
series = "Key Engineering Materials",
publisher = "Trans Tech Publications Ltd",
pages = "23--26",
editor = "Ana, {Ika Dewi} and Kuwat Triyana",
booktitle = "Bioceramics 27",

}

TY - GEN

T1 - Osteoconductivity and bioresorption of an interconnecting porous carbonate apatite with enhanced mechanical strength

AU - Tram, Nguyen Xuan Thanh

AU - Maruta, Michito

AU - Tusru, Kanji

AU - Matsuya, Shigeki

AU - Ishikawa, Kunio

PY - 2016/1/1

Y1 - 2016/1/1

N2 - We have established a processing method to fabricate three-dimensional porous carbonate apatite (CO3Ap) with interconnected porous structure and improved mechanical strength. Briefly, porous CO3Ap materials were produced via phosphorization of porous calcite precursor in hydrothermal condition. In order to make porous calcite precursor, negative replication of modified polyurethane foam template was conducted. In this study, an in vivo behavior of that porous CO3Ap was evaluated. The interconnected porous CO3Ap material was implanted in the tibia of Japanese male rabbits and removed after a period of 6 months. Micro-computed tomography (μ-CT) scanner and histological analysis were used to characterize the bone formation response of the porous CO3Ap. The results suggest that porous CO3Ap with enhanced mechanical strength was not only osteoconductive but also bioresorbable therefore it could be used as bone substitute material.

AB - We have established a processing method to fabricate three-dimensional porous carbonate apatite (CO3Ap) with interconnected porous structure and improved mechanical strength. Briefly, porous CO3Ap materials were produced via phosphorization of porous calcite precursor in hydrothermal condition. In order to make porous calcite precursor, negative replication of modified polyurethane foam template was conducted. In this study, an in vivo behavior of that porous CO3Ap was evaluated. The interconnected porous CO3Ap material was implanted in the tibia of Japanese male rabbits and removed after a period of 6 months. Micro-computed tomography (μ-CT) scanner and histological analysis were used to characterize the bone formation response of the porous CO3Ap. The results suggest that porous CO3Ap with enhanced mechanical strength was not only osteoconductive but also bioresorbable therefore it could be used as bone substitute material.

UR - http://www.scopus.com/inward/record.url?scp=84973473603&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84973473603&partnerID=8YFLogxK

U2 - 10.4028/www.scientific.net/KEM.696.23

DO - 10.4028/www.scientific.net/KEM.696.23

M3 - Conference contribution

AN - SCOPUS:84973473603

SN - 9783035710403

T3 - Key Engineering Materials

SP - 23

EP - 26

BT - Bioceramics 27

A2 - Ana, Ika Dewi

A2 - Triyana, Kuwat

PB - Trans Tech Publications Ltd

ER -