Outcome of a pulmonary metastasectomy for an orthopedic malignancy

Ryuichi Suemitsu, Ichiro Yoshino, Makiko Tomiyasu, Kaoru Ondo, Hitoshi Ueda, Yukihide Iwamoto, Yoshihiko Maehara

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: The purpose of this study was to examine the pulmonary metastatic results in patients with orthopedic malignancies. Methods: Forty-three consecutive patients who underwent a resection of a pulmonary metastasis from an orthopedic malignancy in our hospital were retrospectively investigated. The survival following the resection of a pulmonary metastatic tumor was then analyzed using the Kaplan-Meier method. The impact of clinicopathologic variables on the prognosis including gender, patient age, primary tumor type, the number of the pulmonary metastases, the number of metastasectomies, the operation-era, and the disease-free interval was examined by the Logrank test and Cox's proportional hazards model. Results: The 5-year overall survivals after a pulmonary metastasectomy were 20.7%. A univariate analysis revealed a significant benefit in the post-metastasectomy survival based on the patients age and the disease-free interval. A multivariate analysis demonstrated patient age to be an independent factor for the prognosis with a hazard ratio of 4.873 (p=0.0373). When only young (less than 40 years of age) patients were investigated, the histologic type was revealed to be related to the prognosis (p=0.0004). Conclusion: Pulmonary metastasis from soft tissue tumors is considered to lead to a poor prognosis for younger patients and a metastasectomy for such patients should be considered as one of the potentially effective treatments.

Original languageEnglish
Pages (from-to)420-425
Number of pages6
JournalJapanese Journal of Thoracic and Cardiovascular Surgery
Volume53
Issue number8
DOIs
Publication statusPublished - Aug 2005

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Metastasectomy
Orthopedics
Lung
Neoplasms
Neoplasm Metastasis
Survival
Proportional Hazards Models
Multivariate Analysis

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Suemitsu, R., Yoshino, I., Tomiyasu, M., Ondo, K., Ueda, H., Iwamoto, Y., & Maehara, Y. (2005). Outcome of a pulmonary metastasectomy for an orthopedic malignancy. Japanese Journal of Thoracic and Cardiovascular Surgery, 53(8), 420-425. https://doi.org/10.1007/s11748-005-0077-8

Outcome of a pulmonary metastasectomy for an orthopedic malignancy. / Suemitsu, Ryuichi; Yoshino, Ichiro; Tomiyasu, Makiko; Ondo, Kaoru; Ueda, Hitoshi; Iwamoto, Yukihide; Maehara, Yoshihiko.

In: Japanese Journal of Thoracic and Cardiovascular Surgery, Vol. 53, No. 8, 08.2005, p. 420-425.

Research output: Contribution to journalArticle

Suemitsu, R, Yoshino, I, Tomiyasu, M, Ondo, K, Ueda, H, Iwamoto, Y & Maehara, Y 2005, 'Outcome of a pulmonary metastasectomy for an orthopedic malignancy', Japanese Journal of Thoracic and Cardiovascular Surgery, vol. 53, no. 8, pp. 420-425. https://doi.org/10.1007/s11748-005-0077-8
Suemitsu, Ryuichi ; Yoshino, Ichiro ; Tomiyasu, Makiko ; Ondo, Kaoru ; Ueda, Hitoshi ; Iwamoto, Yukihide ; Maehara, Yoshihiko. / Outcome of a pulmonary metastasectomy for an orthopedic malignancy. In: Japanese Journal of Thoracic and Cardiovascular Surgery. 2005 ; Vol. 53, No. 8. pp. 420-425.
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