Oxidative stress in cardiac and skeletal muscle dysfunction associated with diabetes mellitus

Hiroyuki Tsutsui, Shintaro Kinugawa, Shouji Matsushima, Takashi Yokota

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

Diabetes mellitus increases the risk of heart failure independently of underlying coronary artery disease. It also causes skeletal muscle dysfunction, which is responsible for reduced exercise capacity commonly seen in heart failure. The underlying pathogenesis is partially understood. Several factors may contribute to the development of cardiac and skeletal muscle dysfunction in heart failure and diabetes mellitus. Based on the findings in animal models, this review discusses the role of oxidative stress that may be involved in the development and progression of cardiac and skeletal dysfunction associated with diabetes.

Original languageEnglish
Pages (from-to)68-71
Number of pages4
JournalJournal of Clinical Biochemistry and Nutrition
Volume48
Issue number1
DOIs
Publication statusPublished - Jan 1 2011
Externally publishedYes

Fingerprint

Oxidative stress
Medical problems
Muscle
Myocardium
Diabetes Mellitus
Skeletal Muscle
Oxidative Stress
Heart Failure
Coronary Artery Disease
Animals
Animal Models

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Clinical Biochemistry

Cite this

Oxidative stress in cardiac and skeletal muscle dysfunction associated with diabetes mellitus. / Tsutsui, Hiroyuki; Kinugawa, Shintaro; Matsushima, Shouji; Yokota, Takashi.

In: Journal of Clinical Biochemistry and Nutrition, Vol. 48, No. 1, 01.01.2011, p. 68-71.

Research output: Contribution to journalReview article

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