Palindromic repetitive DNA elements with coding potential in Methanocaldococcus jannaschii

Mikita Suyama, Warren C. Lathe, Peer Bork

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We have identified 141 novel palindromic repetitive elements in the genome of euryarchaeon Methanocaldococcus jannaschii. The total length of these elements is 14.3 kb, which corresponds to 0.9% of the total genomic sequence and 6.3% of all extragenic regions. The elements can be divided into three groups (MJRE1-3) based on the sequence similarity. The low sequence identity within each of the groups suggests rather old origin of these elements in M. jannaschii. Three MJRE2 elements were located within the protein coding regions without disrupting the coding potential of the host genes, indicating that insertion of repeats might be a widespread mechanism to enhance sequence diversity in coding regions.

Original languageEnglish
Pages (from-to)5281-5286
Number of pages6
JournalFEBS Letters
Volume579
Issue number24
DOIs
Publication statusPublished - Oct 10 2005

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Methanocaldococcus
Genes
Insertional Mutagenesis
DNA
Open Reading Frames
Genome
Proteins

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

Cite this

Palindromic repetitive DNA elements with coding potential in Methanocaldococcus jannaschii. / Suyama, Mikita; Lathe, Warren C.; Bork, Peer.

In: FEBS Letters, Vol. 579, No. 24, 10.10.2005, p. 5281-5286.

Research output: Contribution to journalArticle

Suyama, Mikita ; Lathe, Warren C. ; Bork, Peer. / Palindromic repetitive DNA elements with coding potential in Methanocaldococcus jannaschii. In: FEBS Letters. 2005 ; Vol. 579, No. 24. pp. 5281-5286.
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